Cohen N D, Roussel A J, Lumsden J H, Cohen A C, Grift E, Lewis C
Department of Large Medicine and Surgery, College of Veterinary Medicine, Texan A&M University, College Station 77843-4475.
Can J Vet Res. 1993 Jan;57(1):9-13.
Alterations of acid-base status, and fluid and electrolyte balance subsequent to exercise in Thoroughbred racehorses in North America have not been well-characterized. Des-cribed here are the results of an observational study conducted to characterize changes in fluid and electrolytes following strenuous exercise of 16 Thoroughbreds under routine training conditions. Changes following strenuous exercise were determined for the following variables: serum concentrations of sodium (Na), potassium (K), chloride (Cl) and protein; pH of blood; osmolality of plasma and urine; body weight; and, fractional urinary excretion (FE) of Na, K and Cl. The following changes occurred during exercise: increased concentration of Na in blood; increased FE of Na; decreased concentration of Cl in blood; decreased FE of Cl; increased urinary and plasmal osmolality; weight-loss; decreased pH of blood; and, increased concentration of lactic acid. The concurrent decreased concentration of chloride in plasma and acidemia in these horses differed from the hypochloremic, metabolic alkalosis previously described among endurance horses. Acidemia was attributed to production of lactic acid by anaerobic glycolysis.
北美纯种赛马运动后酸碱状态、液体及电解质平衡的变化尚未得到充分描述。本文描述了一项观察性研究的结果,该研究旨在确定16匹纯种马在常规训练条件下剧烈运动后液体和电解质的变化。针对以下变量确定了剧烈运动后的变化:血清钠(Na)、钾(K)、氯(Cl)和蛋白质浓度;血液pH值;血浆和尿液渗透压;体重;以及钠、钾和氯的尿排泄分数(FE)。运动过程中发生了以下变化:血液中钠浓度升高;钠的FE升高;血液中氯浓度降低;氯的FE降低;尿液和血浆渗透压升高;体重减轻;血液pH值降低;以及乳酸浓度升高。这些马匹血浆中氯浓度同时降低和酸血症与先前描述的耐力马中的低氯性代谢性碱中毒不同。酸血症归因于无氧糖酵解产生乳酸。