Máxima Obesity Centre, Department of Surgery, Máxima Medical Centre, Veldhoven, /Eindhoven, the Netherlands.
Obes Surg. 2020 Sep;30(9):3394-3401. doi: 10.1007/s11695-020-04574-5.
Primary nonresponse (1NR) - inability to achieve adequate weight loss after surgery - and secondary nonresponse (2NR) - excessive weight regain after initial adequate weight loss after surgery - can occur in up to 25-35% of patients after bariatric surgery. The aim of this study was to explore the variations in both definition as well as management of 1NR and 2NR amongst bariatric surgeons.
An online survey was distributed to all members of the national bariatric societies in the Netherlands and Belgium regarding questions about definition, work-up and treatment of 1NR and 2NR after bariatric surgery.
A total of 45 responses from bariatric surgeons were obtained, representing 32 medical centers that perform bariatric procedures. When assessing 1NR, excess weight loss(EWL) was reported to be used by most respondents(30/45), total body weight loss(TBWL) by 18/45 and body mass index(BMI) by 25/45. A great variation in cut off values was observed. When assessing 2NR, percentage weight gain from the lowest (nadir) weight was preferred most by 22/45 respondents with cut off values varying from 5 to 20%. Most respondents deemed 18 months after initial surgery the most appropriate timeframe to determine 1NR or 2NR.
The current practice regarding primary and secondary nonresponse after bariatric surgery has a wide variety in definitions, work-up and treatment options. Consensus on the definition of 1NR and 2NR is needed to optimize the treatment of bariatric patients.
原发性无应答(1NR)——手术后无法达到足够的减重效果,以及继发性无应答(2NR)——手术后初始充分减重后体重过度反弹,这两种情况在接受减重手术后的患者中可能会发生在多达 25-35%的患者中。本研究旨在探讨减重外科医生对 1NR 和 2NR 的定义以及管理的变化。
一项在线调查被分发给荷兰和比利时全国减重协会的所有成员,询问他们关于手术后 1NR 和 2NR 的定义、检查和治疗的问题。
共收到 45 名减重外科医生的回复,代表了 32 个进行减重手术的医疗中心。在评估 1NR 时,大多数受访者(30/45)报告使用了超重减轻(EWL),18/45 的人使用了总体体重减轻(TBWL),25/45 的人使用了体重指数(BMI)。观察到截止值存在很大差异。在评估 2NR 时,22/45 的受访者首选从最低(最低点)体重增加的百分比,截止值从 5%到 20%不等。大多数受访者认为在初始手术后 18 个月是确定 1NR 或 2NR 的最合适时间框架。
目前,关于减重手术后原发性和继发性无应答的治疗实践在定义、检查和治疗方案方面存在很大差异。需要就 1NR 和 2NR 的定义达成共识,以优化对减重患者的治疗。