Sloan G M, Bolton L L, Miller J H, Reinisch J F, Nichter L S
Division of Plastic Surgery, Childrens Hospital of Los Angeles, University of Southern California, Los Angeles 90027.
Ann Plast Surg. 1988 Sep;21(3):236-41. doi: 10.1097/00000637-198809000-00008.
Vascular malformations, particularly in the absence of cutaneous changes, can be difficult to distinguish from other soft tissue masses in children. We have used technetium-99m-labeled red blood cell scintigraphy to study 47 lesions in 43 children. Thirty-nine lesions showed increased flow and were, therefore, diagnosed as vascular malformations. Subsequent biopsy of 10 of these lesions confirmed that diagnosis. The other 29 lesions with increased flow were followed for 10 months to 5 years and the clinical course was consistent with vascular malformation in every case. Eight lesions showed no increased flow on technetium scan. One of these subsequently proved to be a hemangioma. The others have turned out not to be vascular malformations. Therefore, in our experience, the technetium-99m-labeled red blood cell scan has had 98% sensitivity and 100% specificity in diagnosing vascular malformations in children.
血管畸形，尤其是在没有皮肤改变的情况下，可能很难与儿童的其他软组织肿块区分开来。我们使用锝-99m标记的红细胞闪烁显像技术研究了43名儿童的47个病变。39个病变显示血流增加，因此被诊断为血管畸形。随后对其中10个病变进行活检，证实了该诊断。其他29个血流增加的病变随访了10个月至5年，临床病程在每个病例中均与血管畸形一致。8个病变在锝扫描中未显示血流增加。其中1个后来被证明是血管瘤。其他病变后来被证明不是血管畸形。因此，根据我们的经验，锝-99m标记的红细胞扫描在诊断儿童血管畸形方面具有98%的敏感性和100%的特异性。
