Hagay Z J, Leiberman R J, Katz M, Witznitzer A
Division of Obstetrics and Gynecology, Soroka University Hospital, Beer-Sheva, Israel.
Arch Gynecol Obstet. 1988;243(4):231-4. doi: 10.1007/BF00932273.
A variety of benign liver tumors associated with the use of oral contraceptives has been described. However, there is controversy regarding the possible relation of focal nodular hyperplasia of the liver to oral contraceptive therapy. Over a ten-year period at the Soroka Medical Center, two young women were found to have hepatic tumors diagnosed as focal nodular hyperplasia. In both cases the hepatic nodules were an incidental finding at laparotomy and were thought to be metastatic tumors. The clinical and pathological findings in both cases are reported. The features of focal nodular hyperplasia and its possible relation to oral contraceptive use is discussed.
已描述了多种与口服避孕药使用相关的良性肝脏肿瘤。然而，关于肝脏局灶性结节性增生与口服避孕药治疗之间可能的关系存在争议。在索罗卡医疗中心的十年间，发现两名年轻女性患有被诊断为局灶性结节性增生的肝脏肿瘤。在这两例中，肝脏结节都是剖腹手术时的偶然发现，当时被认为是转移性肿瘤。报告了两例的临床和病理结果。讨论了局灶性结节性增生的特征及其与口服避孕药使用的可能关系。
