Lieberman D A, Keeffe E B, Stenzel P
J Clin Gastroenterol. 1984 Apr;6(2):145-8. doi: 10.1097/00004836-198404000-00009.
Oral contraceptives frequently produce mild hepatocellular dysfunction, but only rarely cause jaundice. The syndrome of oral contraceptive jaundice is usually mild, with rapid resolution upon withdrawal of the drug. We describe a patient who had a severe illness with marked jaundice after one cycle of oral contraceptives. Her symptoms progressively worsened and serum bilirubin increased for almost 3 months after discontinuation of oral contraceptives. Full recovery ultimately occurred. Her severe and prolonged course demonstrates the wide spectrum of oral contraceptive jaundice.
口服避孕药常引起轻度肝细胞功能障碍，但很少导致黄疸。口服避孕药所致黄疸综合征通常较轻，停药后可迅速消退。我们报告一名患者，在服用一个周期口服避孕药后出现严重疾病并伴有明显黄疸。停药后，她的症状逐渐加重，血清胆红素升高持续了近3个月。最终完全康复。她严重且病程迁延的情况表明口服避孕药所致黄疸的表现范围很广。
