Division of Endocrinology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Division of Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Endocr J. 2020 Jul 28;67(7):785-791. doi: 10.1507/endocrj.EJ20-0013. Epub 2020 Apr 2.
Vertebral fracture is the most common type of osteoporotic fracture. However, the prevalence of osteoporosis and osteoporotic vertebral fractures were not explored previously in the United Arab Emirates (UAE). This study aims to describe for the first time the demographic and morphological characteristics of patients with fragility vertebral fractures in the UAE through a retrospective review of the medical records of patients with low-trauma vertebral fractures who visited two tertiary centers during 2011-2016. The sex, age at the time of fracture, nationality, body mass index (BMI), and anatomical fracture location were recorded for each patient. Overall, 143 subjects were diagnosed with low-trauma vertebral fractures in the Emirate of Abu Dhabi during 2011-2016. Of these, 98 were women (68.5%) and 45 were men (31.5%). The overall mean patient age at diagnosis was 62.5 years, and almost half were younger than 65 years. Approximately 60% of the patients were UAE nationals. Fifty-one patients (36.7%) were obese (mean BMI: 35.3 kg/m), and women with vertebral fractures had a significantly higher mean BMI compared with men (p = 0.041). Nearly 40% of men had a normal BMI, compared with 20% of women. Most fractures were compression fractures (77.6%) in the thoracolumbar transition region. In conclusion, patients with fragility vertebral fractures were predominantly female and tended to be overweight or obese, although male patients tended to have a lower BMI than female patients.
脊柱骨折是最常见的骨质疏松性骨折类型。然而,此前在阿拉伯联合酋长国(阿联酋)并未对骨质疏松症和骨质疏松性脊柱骨折的流行情况进行研究。本研究旨在通过对 2011-2016 年期间访问两家三级中心的低创伤性脊柱骨折患者的病历进行回顾性分析,首次描述阿联酋脆性脊柱骨折患者的人口统计学和形态学特征。记录每位患者的性别、骨折时的年龄、国籍、体重指数(BMI)和解剖骨折部位。总体而言,2011-2016 年在阿布扎比酋长国诊断出 143 例低创伤性脊柱骨折患者。其中,98 例为女性(68.5%),45 例为男性(31.5%)。总体而言,患者的平均诊断年龄为 62.5 岁,近一半年龄小于 65 岁。约 60%的患者为阿联酋国民。51 例(36.7%)患者肥胖(平均 BMI:35.3kg/m),与男性相比,患有脊柱骨折的女性 BMI 明显更高(p=0.041)。与女性相比,约 40%的男性 BMI 正常。大多数骨折为胸腰椎过渡区的压缩性骨折(77.6%)。总之,脆性脊柱骨折患者以女性为主,且倾向于超重或肥胖,尽管男性患者的 BMI 往往低于女性患者。