Department of Chemistry, Khoy Branch, Islamic Azad University, Khoy, 58168, Iran.
Massachusetts Eye and Ear and Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, MA, 02139, USA.
Chem Biodivers. 2020 May;17(5):e2000133. doi: 10.1002/cbdv.202000133. Epub 2020 Apr 29.
In this study, we extracted the essential oils of the stem, leaf, and flower of Achillea filipendulina, analyzed them, and studied their antibacterial properties. Of 16, 53, and 35 compounds identified in the stem, leaf, and flowers, respectively, only five are present in all three segments of the plant. The essential oil of the stem was mainly composed of neryl acetate, spathulenol, carvacrol, santolina alcohol, and trans-caryophyllene oxide. However, the main identified components of leaf were 1,8-cineole, camphor, ascaridole, trans-isoascaridole, and piperitone oxide and the main components of the flower oil were ascaridole, trans-isoascaridole, 1,8-cineole, p-cymene, and camphor. The extracted oil from different segments demonstrated varying antibacterial properties against both Gram-positive and Gram-negative bacteria, demonstrated by disk, minimum inhibitory concentration, and minimum bactericidal concentration methods. These suggest that the application of all segments of aerial parts of A. filipendulina may have a better therapeutic effect in fighting pathogenic systems.
在这项研究中,我们提取了小白菊茎、叶和花的精油,对其进行了分析,并研究了它们的抗菌性能。在所鉴定的 16、53 和 35 种化合物中,只有 5 种存在于植物的所有三个部分。茎精油主要由橙花叔醇乙酸酯、斯巴醇、香芹酚、圣草酚和反式石竹烯氧化物组成。然而,叶的主要成分是 1,8-桉叶素、樟脑、ascaridole、反式异ascaridole 和胡椒酮氧化物,花油的主要成分是ascaridole、trans-isoascaridole、1,8-桉叶素、对伞花烃和樟脑。通过圆盘法、最小抑菌浓度法和最小杀菌浓度法,从不同部位提取的油对革兰氏阳性菌和革兰氏阴性菌均显示出不同的抗菌性能。这表明小白菊地上部分所有部位的应用可能在对抗致病系统方面有更好的治疗效果。