生长于尼日利亚的土荆芥精油的挥发性成分及抗菌筛选
Volatile constituents and antibacterial screening of the essential oil of Chenopodium ambrosioides L. growing in Nigeria.
作者信息
Owolabi Moses S, Lajide Labunmi, Oladimeji Matthew O, Setzer William N, Palazzo Maria C, Olowu Rasaq A, Ogundajo Akintayo
机构信息
Department of Chemistry, Lagos State University, P.M.B 001, Ojo, Lagos, Nigeria.
出版信息
Nat Prod Commun. 2009 Jul;4(7):989-92.
The essential oil of the aerial parts of Chenopodium ambrosioides L. has been isolated by hydrodistillation and analyzed using GC-MS. The major components were found to be alpha-terpinene (63.1%), p-cymene (26.4%) and ascaridole (3.9%). The oil displayed no antibacterial activity against either Gram-positive bacteria Bacillus cereus or Staphylococcus aureus, or the Gram-negative bacterium Escherichia coli (MIC=1250 microg/mL). A cluster analysis of C. ambrosioides essential oils reveals at least seven distinct chemotypes: ascaridole, alpha-terpinene, alpha-pinene, p-cymene, carvacrol, alpha-terpinyl acetate, and limonene.
采用水蒸馏法从土荆芥地上部分分离得到挥发油，并利用气相色谱-质谱联用仪（GC-MS）进行分析。结果表明，其主要成分包括α-松油烯（63.1%）、对伞花烃（26.4%）和驱蛔脑（3.9%）。该挥发油对革兰氏阳性菌蜡样芽孢杆菌、金黄色葡萄球菌以及革兰氏阴性菌大肠杆菌均无抗菌活性（最低抑菌浓度MIC = 1250μg/mL）。对土荆芥挥发油的聚类分析显示至少存在七种不同的化学类型：驱蛔脑型、α-松油烯型、α-蒎烯型、对伞花烃型、香芹酚型、乙酸α-萜品酯型和柠檬烯型。
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