Langou R A, Cohen L S
Yale J Biol Med. 1977 Jan-Feb;50(1):59-65.
(1) To maintain systemic blood flow; (2) To reduce cardiac work and tension development; and (3) To increase oxygen availability to the heart. Toward these ends, various devices and techniques have been developed, including several different types of vascular shunts in combination with or without extracorporeal oxygenation of blood, implantable auxiliary ventricle and augmentation of diastolic pressure by direct counter pulsation of blood through femoral cannulae or intra-aortic balloon.The sequenced counter pulsator is an external cardiac assist device being developed for the therapy of low output syndromes. Investigation in the laboratory has shown that it is capable of increasing cardiac output and diastolic systemic pressure with concomitant reduction in left ventricular end-diastolic pressure. Therefore, it appears to be clinically useful in patients with low cardiac output syndromes.
(1)维持全身血流;(2)减少心脏做功和张力发展;(3)增加心脏的氧供应。为实现这些目标,已开发出各种装置和技术,包括几种不同类型的血管分流术,可联合或不联合体外血液氧合、植入式辅助心室以及通过股动脉插管或主动脉内球囊对血液进行直接反搏来增加舒张压。顺序式反搏器是一种正在开发用于治疗低输出综合征的体外心脏辅助装置。实验室研究表明,它能够增加心输出量和舒张期体循环压力,同时降低左心室舒张末期压力。因此,它在低心输出量综合征患者中似乎具有临床应用价值。