Pai I, Mendis S, Murdin L, Touska P, Connor S
Department of Otolaryngology, Guy's and St Thomas' Hospital, London, UK.
Department of Radiology, Guy's and St Thomas' Hospital, London, UK.
J Laryngol Otol. 2020 Apr;134(4):302-310. doi: 10.1017/S0022215120000626. Epub 2020 Apr 3.
Recent developments in magnetic resonance imaging have enabled demonstration of endolymphatic hydrops, and the clinical application of these imaging studies in Ménière's disease is being explored.
To evaluate our centre's experience to date of hydrops magnetic resonance imaging in patients with episodic vertigo.
Magnetic resonance imaging was performed using a high-resolution three-dimensional fluid-attenuated inversion recovery sequence on a 3 Tesla scanner at 4 hours following double-dose gadolinium administration.
The study included 31 patients, 28 of whom had a clinical diagnosis of Ménière's disease. In unilateral Ménière's disease, magnetic resonance imaging was able to lateralise endolymphatic hydrops to the clinically symptomatic ear in all cases. Mild hydrops was often seen in clinically asymptomatic ears.
There is a good correlation between the clinical symptoms and lateralisation of hydropic changes on magnetic resonance imaging. Further refinements of imaging techniques and grading system will likely improve the diagnostic accuracy and clinical utilisation of hydrops magnetic resonance imaging.
磁共振成像的最新进展已能够显示内淋巴积水,并且正在探索这些成像研究在梅尼埃病中的临床应用。
评估我们中心迄今为止对发作性眩晕患者进行积水磁共振成像的经验。
在给予双倍剂量钆剂4小时后,使用3特斯拉扫描仪上的高分辨率三维液体衰减反转恢复序列进行磁共振成像。
该研究纳入了31例患者,其中28例临床诊断为梅尼埃病。在单侧梅尼埃病中,磁共振成像能够在所有病例中将内淋巴积水定位于临床有症状的耳朵侧。在临床无症状的耳朵中经常可见轻度积水。
临床症状与磁共振成像上积水变化的定位之间存在良好的相关性。成像技术和分级系统的进一步完善可能会提高积水磁共振成像的诊断准确性和临床应用价值。