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表现为脑积水的颅底动脉瘤样骨囊肿:一名儿科患者中被伽玛刀立体定向放射外科手术消除的进行性残留物

Skull base aneurysmal bone cyst presenting with hydrocephalus: progressive residuum obliterated by Gamma Knife stereotactic radiosurgery in a pediatric patient.

作者信息

Tse George H, Jiang Feng Y, Radatz Matthias W R, Sinha Saurabh, Zaki Hesham

机构信息

1Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, United Kingdom.

2Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

J Neurosurg Pediatr. 2020 Apr 3;26(1):76-81. doi: 10.3171/2020.2.PEDS19755. Print 2020 Jul 1.

Abstract

Aneurysmal bone cysts (ABCs) are an uncommon entity predominantly encountered in the pediatric population. The skull is rarely involved, but these cysts have been reported to arise in the skull base. Traditional treatment has been with surgery alone; however, there is a gathering body of literature that reports alternative treatments that can achieve long-term disease-free survival. However, these therapies are predominantly directed at peripheral skeletal lesions. To the authors' knowledge, this report is the first to describe long-term follow-up of the efficacy of Gamma Knife stereotactic radiosurgery for treatment of ABC residuum in the skull base that resulted in long-term patient stability and likely ABC obliteration.

摘要

骨囊肿(ABCs)是一种罕见的病变,主要见于儿童人群。颅骨很少受累,但据报道这些囊肿可发生于颅底。传统治疗方法一直是单纯手术;然而,越来越多的文献报道了可实现长期无病生存的替代治疗方法。然而,这些治疗主要针对外周骨骼病变。据作者所知,本报告首次描述了伽玛刀立体定向放射外科治疗颅底ABC残留灶疗效的长期随访情况,该治疗使患者长期保持稳定,且可能使ABC消失。

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