相似文献
1
Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967.
Int J Mol Sci. 2020 Apr 1;21(7):2454. doi: 10.3390/ijms21072454.
2
Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.
Brain. 2016 Aug;139(Pt 8):2164-81. doi: 10.1093/brain/aww129. Epub 2016 Jun 5.
3
Prax330 reduces persistent and resurgent sodium channel currents and neuronal hyperexcitability of subiculum neurons in a mouse model of SCN8A epileptic encephalopathy.
Neuropharmacology. 2019 Nov 1;158:107699. doi: 10.1016/j.neuropharm.2019.107699. Epub 2019 Jul 3.
4
The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.
Epilepsia. 2018 Jun;59(6):1166-1176. doi: 10.1111/epi.14196. Epub 2018 May 21.
5
Resurgent and Gating Pore Currents Induced by Epilepsy Mutations.
eNeuro. 2019 Oct 16;6(5). doi: 10.1523/ENEURO.0141-19.2019. Print 2019 Sep/Oct.
6
Antiepileptic activity of preferential inhibitors of persistent sodium current.
Epilepsia. 2014 Aug;55(8):1274-83. doi: 10.1111/epi.12657. Epub 2014 May 23.
7
Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene.
J Headache Pain. 2019 Nov 15;20(1):107. doi: 10.1186/s10194-019-1056-2.
8
Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide.
Mol Pharmacol. 2011 Oct;80(4):724-34. doi: 10.1124/mol.111.072751. Epub 2011 Jul 25.
9
Increased Resurgent Sodium Currents in Nav1.8 Contribute to Nociceptive Sensory Neuron Hyperexcitability Associated with Peripheral Neuropathies.
J Neurosci. 2019 Feb 20;39(8):1539-1550. doi: 10.1523/JNEUROSCI.0468-18.2018. Epub 2019 Jan 7.
10
Inhibitory effects of cannabidiol on voltage-dependent sodium currents.
J Biol Chem. 2018 Oct 26;293(43):16546-16558. doi: 10.1074/jbc.RA118.004929. Epub 2018 Sep 14.
引用本文的文献
1
A MULTI-HIT MODEL OF LONG COVID PATHOPHYSIOLOGY: THE INTERACTION BETWEEN IMMUNE TRIGGERS AND NERVOUS SYSTEM SIGNALING.
Trans Am Clin Climatol Assoc. 2024;134:149-164.
2
Persistent sodium currents in neurons: potential mechanisms and pharmacological blockers.
Pflugers Arch. 2024 Oct;476(10):1445-1473. doi: 10.1007/s00424-024-02980-7. Epub 2024 Jul 5.
3
Interplay between endocannabinoids and dopamine in the basal ganglia: implications for pain in Parkinson's disease.
J Anesth Analg Crit Care. 2024 May 14;4(1):33. doi: 10.1186/s44158-024-00169-z.
4
A structural atlas of druggable sites on Na channels.
Channels (Austin). 2024 Dec;18(1):2287832. doi: 10.1080/19336950.2023.2287832. Epub 2023 Nov 30.
5
Cannabidiol inhibits Na channels through two distinct binding sites.
Nat Commun. 2023 Jun 17;14(1):3613. doi: 10.1038/s41467-023-39307-6.
6
The Polypharmacological Effects of Cannabidiol.
Molecules. 2023 Apr 6;28(7):3271. doi: 10.3390/molecules28073271.
7
Advances and Challenges of Cannabidiol as an Anti-Seizure Strategy: Preclinical Evidence.
Int J Mol Sci. 2022 Dec 19;23(24):16181. doi: 10.3390/ijms232416181.
8
Eslicarbazepine, but Not Lamotrigine or Ranolazine, Shows Anticonvulsant Efficacy in Carbamazepine-Resistant Rats Developed by Window-Pentylenetetrazole Kindling.
Brain Sci. 2022 May 11;12(5):629. doi: 10.3390/brainsci12050629.
9
Cannabidiol activates neuronal Kv7 channels.
Elife. 2022 Feb 18;11:e73246. doi: 10.7554/eLife.73246.
10
Channelopathy of Dravet Syndrome and Potential Neuroprotective Effects of Cannabidiol.
J Cent Nerv Syst Dis. 2021 Dec 20;13:11795735211048045. doi: 10.1177/11795735211048045. eCollection 2021.
本文引用的文献
1
Efficacy of cannabidiol in subjects with refractory epilepsy relative to concomitant use of clobazam.
Epilepsy Res. 2020 Feb;160:106263. doi: 10.1016/j.eplepsyres.2019.106263. Epub 2019 Dec 28.
2
Resurgent and Gating Pore Currents Induced by Epilepsy Mutations.
eNeuro. 2019 Oct 16;6(5). doi: 10.1523/ENEURO.0141-19.2019. Print 2019 Sep/Oct.
3
Prax330 reduces persistent and resurgent sodium channel currents and neuronal hyperexcitability of subiculum neurons in a mouse model of SCN8A epileptic encephalopathy.
Neuropharmacology. 2019 Nov 1;158:107699. doi: 10.1016/j.neuropharm.2019.107699. Epub 2019 Jul 3.
4
Cannabidiol: Recent advances and new insights for neuropsychiatric disorders treatment.
Life Sci. 2019 May 1;224:120-127. doi: 10.1016/j.lfs.2019.03.053. Epub 2019 Mar 22.
5
Increased Resurgent Sodium Currents in Nav1.8 Contribute to Nociceptive Sensory Neuron Hyperexcitability Associated with Peripheral Neuropathies.
J Neurosci. 2019 Feb 20;39(8):1539-1550. doi: 10.1523/JNEUROSCI.0468-18.2018. Epub 2019 Jan 7.
6
Prominent role of forebrain excitatory neurons in SCN8A encephalopathy.
Brain. 2019 Feb 1;142(2):362-375. doi: 10.1093/brain/awy324.
7
Inhibitory effects of cannabidiol on voltage-dependent sodium currents.
J Biol Chem. 2018 Oct 26;293(43):16546-16558. doi: 10.1074/jbc.RA118.004929. Epub 2018 Sep 14.
8
Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study.
Epilepsy Behav. 2018 Oct;87:131-136. doi: 10.1016/j.yebeh.2018.07.020. Epub 2018 Aug 9.
9
Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results.
Epilepsia. 2018 Aug;59(8):1540-1548. doi: 10.1111/epi.14477. Epub 2018 Jul 12.
10
Dynamic action potential clamp predicts functional separation in mild familial and severe de novo forms of epilepsy.
Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5516-E5525. doi: 10.1073/pnas.1800077115. Epub 2018 May 29.
Zotero 插件
