Le Roux Linda, Ménard Olivia, Chacon Raphaël, Dupont Didier, Jeantet Romain, Deglaire Amélie, Nau Françoise
Sill Dairy International, Raden, 29860 Plouvien, France.
STLO, INRAE, AGROCAMPUS OUEST, 35042 Rennes, France.
Foods. 2020 Mar 20;9(3):362. doi: 10.3390/foods9030362.
Infant formulas (IFs) are used as substitutes for human milk and are mostly based on cow milk proteins. For sustainability reasons, animal protein alternatives in food are increasingly being considered, as plant proteins offer interesting nutritional and functional benefits for the development of innovative IFs. This study aimed to assess how a partial substitution (50%) of dairy proteins with faba bean and pea proteins influenced the digestibility of IFs under simulated dynamic in vitro digestion, which were set up to mimic infant digestion. Pea- and faba bean-based IFs (PIF and FIF, respectively) have led to a faster aggregation than the reference milk-based IF (RIF) in the gastric compartment; that did not affect the digesta microstructure at the end of digestion. The extent of proteolysis was estimated via the hydrolysis degree, which was the highest for FIF (73%) and the lowest for RIF (50%). Finally, it was apparent that in vitro protein digestibility and protein digestibility-corrected amino acid score (PDCAAS)-like scores were similar for RIF and FIF (90% digestibility; 75% PDCAAS), lower for PIF (75%; 67%). Therefore, this study confirms that faba bean proteins could be a good candidate for partial substitution of whey proteins in IFs from a nutritional point of view, provided that these in vitro results are confirmed in vivo.
婴儿配方奶粉（IFs）被用作母乳替代品，主要以牛奶蛋白为基础。出于可持续发展的原因，食品中的动物蛋白替代品越来越受到关注，因为植物蛋白为创新型婴儿配方奶粉的开发提供了有趣的营养和功能益处。本研究旨在评估用蚕豆蛋白和豌豆蛋白部分替代（50%）乳制品蛋白如何影响在模拟动态体外消化条件下婴儿配方奶粉的消化率，该模拟消化条件旨在模拟婴儿消化过程。基于豌豆和蚕豆的婴儿配方奶粉（分别为PIF和FIF）在胃部比参考牛奶基婴儿配方奶粉（RIF）导致更快的聚集；这在消化结束时并未影响消化物的微观结构。通过水解度估计蛋白水解程度，其中FIF最高（73%），RIF最低（50%）。最后，很明显，RIF和FIF的体外蛋白质消化率和蛋白质消化率校正氨基酸评分（PDCAAS）样评分相似（消化率90%；PDCAAS 75%），PIF较低（75%；67%）。因此，本研究证实，从营养角度来看，蚕豆蛋白可能是婴儿配方奶粉中部分替代乳清蛋白的良好候选者，前提是这些体外结果在体内得到证实。
