Toutain P L, Oukessou M, Autefage A, Alvinerie M
INRA, Station de Pharmacologie, Toulouse, France.
Domest Anim Endocrinol. 1988 Jan;5(1):55-9. doi: 10.1016/0739-7240(88)90026-4.
Using a specific high-performance liquid chromatographic technique, plasma hydrocortisone values were measured hourly in 6 horses and every 10 minutes in 4 horses over 24 hours. Both circadian and episodic variation was observed. The mean plasma hydrocortisone concentration was a maximum of 58.8 +/- 9.54 ng/ml at 9.19 +/- 0.59 hr and a minimum of 27.85 +/- 6.85 g/ml at 21.19 +/- 0.59 hr. The number of episodes of secretion was 10.0 +/- 1.41; the mean amplitude and duration of peak were 26.21 +/- 3.71 ng/ml and 105.25 +/- 21.24 min respectively.
采用特定的高效液相色谱技术，对6匹马每小时、4匹马每10分钟测定一次血浆氢化可的松值，持续24小时。观察到了昼夜节律和 episodic 变化。血浆氢化可的松平均浓度在9.19±0.59小时达到最高值58.8±9.54纳克/毫升，在21.19±0.59小时达到最低值27.85±6.85微克/毫升。分泌发作次数为10.0±1.41次；峰值的平均幅度和持续时间分别为26.21±3.71纳克/毫升和105.25±21.24分钟。 （注：原文中“27.85 +/- 6.85 g/ml”可能有误，这里按“微克/毫升”翻译）
