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预测急诊科老年患者住院和延长住院时间:PRO-AGE 评分系统。

Predicting Hospital Admission and Prolonged Length of Stay in Older Adults in the Emergency Department: The PRO-AGE Scoring System.

机构信息

Geriatric Emergency Department, Hospital Sirio-Libanes, São Paulo, SP, Brazil.

Geriatric Emergency Department, Hospital Sirio-Libanes, São Paulo, SP, Brazil; Geriatric Center for Advanced Medicine, Hospital Sirio-Libanês, São Paulo, SP, Brazil.

出版信息

Ann Emerg Med. 2020 Sep;76(3):255-265. doi: 10.1016/j.annemergmed.2020.01.010. Epub 2020 Mar 31.

Abstract

STUDY OBJECTIVE

We developed prediction models for hospital admission and prolonged length of stay in older adults admitted from the emergency department (ED).

METHODS

This was a retrospective cohort study of patients aged 70 years or older who visited a geriatric ED in Brazil (N=5,025 visits). We randomly allocated participants to derivation and validation samples in a 2:1 ratio. We then selected 21 variables based on their clinical relevance and generated models to predict the following outcomes: hospital admission and prolonged length of stay, defined as the upper tertile of hospital stay. We used backward stepwise logistic regressions to select our final predictors and developed risk scoring systems based on the relative values of their β coefficients.

RESULTS

Overall, 57% of the participants were women, 31% were hospitalized, and 1% died in the hospital. The upper tertile of hospital stay was greater than 7 days. Hospital admission was best predicted by a model including male sex, aged 90 years or older, hospitalization in the previous 6 months, weight loss greater than or equal to 5% in the previous year, acute mental alteration, and acute functional decline. The prediction of prolonged length of stay retained the same variables, except male sex, which was substituted for fatigue. The final scoring system reached areas under the receiver operating characteristic curve of 0.74 for hospital admission and 0.79 for prolonged length of stay, and their accuracies were confirmed in the validation models.

CONCLUSION

The PRO-AGE scoring system predicted hospital admission and prolonged length of stay in older adults with good accuracy, using a simple approach and only 7 easily obtained clinical variables.

摘要

研究目的

我们开发了预测模型,用于预测从急诊科(ED)入院的老年患者的住院和住院时间延长。

方法

这是一项回顾性队列研究,研究对象为巴西老年 ED 就诊的 70 岁及以上患者(共 5025 例就诊)。我们将参与者随机分为推导和验证样本,比例为 2:1。然后,我们根据临床相关性选择了 21 个变量,并生成了预测以下结果的模型:住院和住院时间延长,定义为住院时间的上三分位。我们使用向后逐步逻辑回归选择最终预测因子,并基于其β系数的相对值开发风险评分系统。

结果

总体而言,参与者中 57%为女性,31%住院,1%在医院死亡。住院时间的上三分位数大于 7 天。包括男性、年龄 90 岁或以上、过去 6 个月住院、过去 1 年体重减轻大于或等于 5%、急性精神改变和急性功能下降在内的模型最能预测住院。延长住院时间的预测保留了相同的变量,除了用疲劳代替了男性。最终的评分系统在入院和延长住院时间的接收者操作特征曲线下面积分别达到 0.74 和 0.79,在验证模型中也得到了验证。

结论

PRO-AGE 评分系统使用简单的方法和仅 7 个易于获得的临床变量,对老年患者的住院和延长住院时间具有良好的预测准确性。

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