• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

CRISPR-based technology to silence the expression of IncRNAs.

作者信息

Phelan James D, Staudt Louis M

机构信息

Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892

出版信息

Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8225-8227. doi: 10.1073/pnas.2003702117. Epub 2020 Apr 3.

DOI:10.1073/pnas.2003702117
PMID:32245807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7165436/
Abstract
摘要

相似文献

1
CRISPR-based technology to silence the expression of IncRNAs.基于CRISPR的技术使长链非编码RNA的表达沉默。
Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8225-8227. doi: 10.1073/pnas.2003702117. Epub 2020 Apr 3.
2
[Advances in application of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 system in stem cells research].成簇规律间隔短回文重复序列(CRISPR)/CRISPR相关蛋白9系统在干细胞研究中的应用进展
Zhonghua Shao Shang Za Zhi. 2018 Apr 20;34(4):253-256. doi: 10.3760/cma.j.issn.1009-2587.2018.04.013.
3
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas Advancement in Molecular Diagnostics and Signal Readout Approaches.簇状规律间隔短回文重复序列 (CRISPR)/Cas 在分子诊断和信号读出方法中的进展。
J Mol Diagn. 2021 Nov;23(11):1433-1442. doi: 10.1016/j.jmoldx.2021.07.025. Epub 2021 Aug 25.
4
Assembling the Streptococcus thermophilus clustered regularly interspaced short palindromic repeats (CRISPR) array for multiplex DNA targeting.组装嗜热链球菌成簇规律间隔短回文重复序列(CRISPR)阵列以实现多重DNA靶向。
Anal Biochem. 2015 Jun 1;478:131-3. doi: 10.1016/j.ab.2015.02.028. Epub 2015 Mar 6.
5
[Application of clustered regularly interspaced short palindromic repeats- associated protein 9 gene editing technology for treatment of HBV infection].[成簇规律间隔短回文重复序列相关蛋白9基因编辑技术在治疗乙型肝炎病毒感染中的应用]
Zhonghua Gan Zang Bing Za Zhi. 2018 Nov 20;26(11):860-864. doi: 10.3760/cma.j.issn.1007-3418.2018.11.012.
6
[Research advances on the development and application of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein system].成簇规律间隔短回文重复序列(CRISPR)/CRISPR相关蛋白系统的开发与应用研究进展
Zhonghua Shao Shang Za Zhi. 2021 Jul 20;37(7):681-687. doi: 10.3760/cma.j.cn501120-20200329-00201.
7
Strategies for Optimization of the Clustered Regularly Interspaced Short Palindromic Repeat-Based Genome Editing System for Enhanced Editing Specificity.优化基于成簇规律间隔短回文重复序列的基因组编辑系统以提高编辑特异性的策略
Hum Gene Ther. 2022 Apr;33(7-8):358-370. doi: 10.1089/hum.2021.283. Epub 2022 Mar 1.
8
Survey of clustered regularly interspaced short palindromic repeats and their associated Cas proteins (CRISPR/Cas) systems in multiple sequenced strains of Klebsiella pneumoniae.肺炎克雷伯菌多个测序菌株中规律成簇间隔短回文重复序列及其相关Cas蛋白(CRISPR/Cas)系统的调查
BMC Res Notes. 2015 Aug 4;8:332. doi: 10.1186/s13104-015-1285-7.
9
Advances in Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Diagnostic Assays Assisted by Micro/Nanotechnologies.基于簇状、规律间隔短回文重复序列(CRISPR)的微/纳米技术辅助诊断检测的进展。
ACS Nano. 2021 May 25;15(5):7848-7859. doi: 10.1021/acsnano.1c02372. Epub 2021 May 7.
10
Considerations for Cardiac CRISPR.心脏CRISPR的考量因素。
Circ Res. 2017 Oct 27;121(10):1111-1112. doi: 10.1161/CIRCRESAHA.117.311974.

引用本文的文献

1
CRISPRepi: a multi-omic atlas for CRISPR-based epigenome editing.CRISPRepi:基于CRISPR的表观基因组编辑的多组学图谱。
Nucleic Acids Res. 2025 Jan 6;53(D1):D901-D913. doi: 10.1093/nar/gkae1039.
2
Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets.非编码 RNA 在 SARS-CoV-2 感染中的表达:发病机制、临床意义和治疗靶点。
Signal Transduct Target Ther. 2023 Dec 6;8(1):441. doi: 10.1038/s41392-023-01669-0.
3
High-Throughput Identification, Modeling, and Analysis of Cancer Driver Genes In Vivo.高通量鉴定、建模和分析体内癌症驱动基因。
Cold Spring Harb Perspect Med. 2023 Jul 5;13(7):a041382. doi: 10.1101/cshperspect.a041382.
4
Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages.CRISPR-Cas9 靶向蛋白编码基因和长非编码 RNA 的双向导 RNA 筛选在人 B 细胞向巨噬细胞转分化中的作用
BMC Genomics. 2022 May 26;23(1):402. doi: 10.1186/s12864-022-08612-7.
5
Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology.长链非编码RNA和微小RNA作为心脏肿瘤学中的关键调节因子。
Cell Biosci. 2022 Mar 4;12(1):24. doi: 10.1186/s13578-022-00757-y.
6
CRISPR-Based Approaches for the High-Throughput Characterization of Long Non-Coding RNAs.基于CRISPR的长链非编码RNA高通量表征方法
Noncoding RNA. 2021 Dec 13;7(4):79. doi: 10.3390/ncrna7040079.
7
What sequencing technologies can teach us about innate immunity.测序技术能告诉我们哪些关于先天免疫的知识。
Immunol Rev. 2022 Jan;305(1):9-28. doi: 10.1111/imr.13033. Epub 2021 Nov 7.
8
A new era in functional genomics screens.功能基因组学筛选的新时代。
Nat Rev Genet. 2022 Feb;23(2):89-103. doi: 10.1038/s41576-021-00409-w. Epub 2021 Sep 20.
9
From Junk to Function: LncRNAs in CNS Health and Disease.从无用之物到发挥功能:中枢神经系统健康与疾病中的长链非编码RNA
Front Mol Neurosci. 2021 Jul 19;14:714768. doi: 10.3389/fnmol.2021.714768. eCollection 2021.

本文引用的文献

1
An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation.一种由 MXD1 衍生的抑制肽可识别 MYC 驱动的细胞增殖的非编码介质。
Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6571-6579. doi: 10.1073/pnas.1921786117. Epub 2020 Mar 10.
2
Pervasive functional translation of noncanonical human open reading frames.广泛存在的非规范人类开放阅读框的功能翻译。
Science. 2020 Mar 6;367(6482):1140-1146. doi: 10.1126/science.aay0262.
3
STAT3-induced upregulation of lncRNA SNHG17 predicts a poor prognosis of melanoma and promotes cell proliferation and metastasis through regulating PI3K-AKT pathway.STAT3 诱导的 lncRNA SNHG17 上调预示着黑色素瘤预后不良,并通过调节 PI3K-AKT 通路促进细胞增殖和转移。
Eur Rev Med Pharmacol Sci. 2019 Sep;23(18):8000-8010. doi: 10.26355/eurrev_201909_19016.
4
Pathogenic B-cell receptor signaling in lymphoid malignancies: New insights to improve treatment.淋巴恶性肿瘤中致病性 B 细胞受体信号转导:改善治疗的新见解。
Immunol Rev. 2019 Sep;291(1):190-213. doi: 10.1111/imr.12792.
5
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.长链非编码 RNA 基因 PVT1 的启动子是一种肿瘤抑制性 DNA 边界元件。
Cell. 2018 May 31;173(6):1398-1412.e22. doi: 10.1016/j.cell.2018.03.068. Epub 2018 May 3.
6
Defining a Cancer Dependency Map.定义癌症依赖图谱。
Cell. 2017 Jul 27;170(3):564-576.e16. doi: 10.1016/j.cell.2017.06.010.
7
Immunobiology of Long Noncoding RNAs.长链非编码RNA的免疫生物学
Annu Rev Immunol. 2017 Apr 26;35:177-198. doi: 10.1146/annurev-immunol-041015-055459. Epub 2017 Jan 11.
8
High-resolution interrogation of functional elements in the noncoding genome.非编码基因组中功能元件的高分辨率分析。
Science. 2016 Sep 30;353(6307):1545-1549. doi: 10.1126/science.aaf7613.
9
Identification and characterization of essential genes in the human genome.人类基因组中必需基因的鉴定与表征
Science. 2015 Nov 27;350(6264):1096-101. doi: 10.1126/science.aac7041. Epub 2015 Oct 15.
10
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.通过工程化的CRISPR-Cas9复合物进行全基因组规模的转录激活
Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10.