HIV 治疗知识在“治疗即预防”（TasP）背景下的应用。
HIV Treatment Knowledge in the Context of "Treatment as Prevention" (TasP).
机构信息
Division on Substance Use Disorders, Department of Psychiatry, Columbia University Irving Medical Center at New York State Psychiatric Institute, 1051 Riverside Drive, Box 120, New York, NY, 10032, USA.
Division of Gender, Sexuality, and Health, Department of Psychiatry, HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University, New York, NY, USA.
出版信息
AIDS Behav. 2020 Oct;24(10):2984-2994. doi: 10.1007/s10461-020-02849-7.
According to 2012 universal ART guidelines, as part of "treatment as prevention" (TasP), all people living with HIV (PLWH) should immediately initiate antiretroviral therapy post-diagnosis to facilitate viral suppression. PLWH who are virally suppressed have no risk of sexually transmitting HIV. This study used descriptive analysis of quantitative data (N = 99) and thematic analysis of qualitative interviews (n = 36) to compare participants recruited from a hospital-based detoxification (detox) unit, largely diagnosed with HIV pre-2012 (n = 63) vs. those recruited from public, urban sexual health clinics (SHCs), mainly diagnosed in 2012 or later (n = 36). Detox participants were significantly more knowledgeable than SHC participants about HIV treatment, except regarding TasP. SHC participants' desire for rapid linkage to care and ART initiation was in line with 2012 universal ART guidelines and TasP messaging regarding viral suppression. More targeted messaging to PLWH pre-2012 could ensure that all PLWH benefit from scientific advances in HIV treatment.
根据 2012 年普遍接受的抗逆转录病毒治疗（ART）指南，作为“治疗即预防”（TasP）的一部分，所有艾滋病毒感染者（PLWH）都应在诊断后立即开始接受抗逆转录病毒治疗，以促进病毒抑制。病毒得到抑制的 PLWH 没有通过性传播 HIV 的风险。本研究使用定量数据的描述性分析（N=99）和定性访谈的主题分析（n=36），比较了从医院戒毒（detox）单位招募的参与者（主要在 2012 年之前诊断出 HIV）与从公共、城市性健康诊所（SHC）招募的参与者（主要在 2012 年或之后诊断出 HIV）。与 SHC 参与者相比，戒毒参与者在 HIV 治疗方面的知识明显更为丰富，除了 TasP 方面。SHC 参与者希望快速获得治疗和开始接受 ART，这符合 2012 年普遍接受的 ART 指南和 TasP 关于病毒抑制的信息。对 2012 年之前的 PLWH 进行更有针对性的宣传，可以确保所有 PLWH 受益于 HIV 治疗方面的科学进步。
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