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有脓毒性关节炎病史的患者行全膝关节置换术是否具有更高的翻修手术风险?一项单中心研究。

Are Patients With a History of Septic Arthritis Undergoing Total Knee Arthroplasty at Higher Risk for Revision Surgery? A Single-Center Study.

机构信息

Department of Joint Surgery, Helios ENDO-Klinik Hamburg, Hamburg, Germany.

Department of Orthopedics, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

出版信息

J Arthroplasty. 2020 Jul;35(7):1857-1861. doi: 10.1016/j.arth.2020.02.065. Epub 2020 Mar 6.

Abstract

BACKGROUND

The decision to perform a total knee arthroplasty (TKA) on a previously infected knee is made complicated by the higher risk for both a periprosthetic joint infection (PJI) and early failure. There is currently no standard in the treatment strategy for this group of patients. We here report the outcomes of performing a primary TKA on patients with a prior septic knee arthritis. The aim of our study is to analyze the survival rates of patients with a history of septic arthritis undergoing TKA.

METHODS

From 2010 to 2018, all patients treated in our institution with a minimum follow-up of 1 year, who have previous histories of knee joint infections and underwent a primary TKA were included in the study. All patients underwent the same surgical protocol and were given systemic and local antibiotic treatment.

RESULTS

Of the 68 knees, there were 4 surgical revisions (5.9%). These included 2 septic revisions due to PJI (2.9%), 1 open arthrolysis for arthrofibrosis (1.5%), and 1 aseptic revision for implant loosening (1.5%). Sixty-four (64) knees (94%) had survived without any surgical interventions and the Kaplan-Meier analysis demonstrated an overall survivorship free from PJI of 97.1% at a mean of 5 years (range 1-9, standard deviation ±2.5 years).

CONCLUSION

TKA is a suitable option for patients with a prior septic arthritis of the knee, provided that proper surgical technique and the utilization of systemic and local antibiotics are employed.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

对于曾经感染过的膝关节,进行全膝关节置换术(TKA)的决策变得复杂,因为发生假体周围关节感染(PJI)和早期失败的风险更高。目前,针对这组患者,尚无标准的治疗策略。我们在此报告对先前患有感染性膝关节炎的患者进行初次 TKA 的结果。我们研究的目的是分析既往患有感染性关节炎接受 TKA 治疗的患者的生存率。

方法

2010 年至 2018 年,我们机构治疗的所有患者均进行了最少 1 年的随访,这些患者有膝关节感染病史,并接受了初次 TKA。所有患者均采用相同的手术方案,并接受了全身和局部抗生素治疗。

结果

在 68 个膝关节中,有 4 例手术翻修(5.9%)。其中包括 2 例因 PJI 而进行的感染性翻修(2.9%)、1 例因关节粘连而行的开放性关节松解术(1.5%)和 1 例因假体松动而行的无菌性翻修术(1.5%)。64 个(64 个膝关节)(94%)膝关节未进行任何手术干预而存活,Kaplan-Meier 分析表明,平均 5 年(范围 1-9 年,标准差±2.5 年)时,总体无 PJI 生存率为 97.1%。

结论

对于有膝关节先前感染性关节炎的患者,只要采用适当的手术技术并使用全身和局部抗生素,TKA 是一种合适的选择。

证据等级

III 级,治疗性研究。

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