Sośnik H
Department of Pathomorphology, Wracław District Specialistic Hospital, Poland.
Gegenbaurs Morphol Jahrb. 1988;134(5):733-61.
The size of the testicle (absolute weight, relative weight as the index X, length, and width was measured in 142 late patients aged 17 to 87 a (mean age = 54 a) serving as controls, in 193 deceased patients aged 20 to 81 a (mean age = 47 a) with a history of alcoholism, and in 136 defunct patients aged 30 to 92 a (mean age = 59 a) with cirrhosis. A significant difference in the mean size of the testicles was demonstrated between the cirrhosis group and both the control and alcoholism groups. No statistically significant differences was observed between the control group and the alcoholism group. The degree of acute alcoholic intoxication has no significant effect on the degree of testicular atrophy. Chronic alcoholism exerted a more significant effect on the degree of testicular atrophy than acute alcoholism. Coexistent cirrhosis increased this difference even more. The type of cirrhosis and the degree of its inflammatory activity had no significant influence on the testicular size. Such effect was demonstrated, however, if diffuse fatty infiltration of the cirrhotic liver was present. In the biomorphosis, the greatest mean testicular size was observed in the 4th and 5th decade of life. From the 6th decade on, the testicular size decreased statistically significantly. The curve of the values of the mean testicular size in alcoholism was more flat than in the control group and was situated below it. No statistically significant differences among the values of the testicular size in this curve were found. The testicular size curve in cirrhosis was below both these curves, and a statistically significant difference was found between the 7th and the 9th decades. The mean weight of the testicules in controls, alcoholics, and patients with cirrhosis was 17.58, 16.49, and 13.25 g, respectively, the mean volume was 16.37, 15.34, and 12.21 ml, respectively, the value of the index X was 2.47, 2.52, and 1.97, respectively, the testicular length was 5.05, 4.08, and 3.61 cm, respectively, the width was 2.93, 2.87, and 2.70 cm, respectively.
对142名年龄在17至87岁（平均年龄54岁）的晚期患者作为对照组，193名年龄在20至81岁（平均年龄47岁）有酗酒史的已故患者，以及136名年龄在30至92岁（平均年龄59岁）患有肝硬化的已故患者，测量了睾丸大小（绝对重量、作为指数X的相对重量、长度和宽度）。肝硬化组与对照组和酗酒组之间睾丸平均大小存在显著差异。对照组和酗酒组之间未观察到统计学上的显著差异。急性酒精中毒程度对睾丸萎缩程度无显著影响。慢性酒精中毒对睾丸萎缩程度的影响比急性酒精中毒更显著。并存的肝硬化使这种差异更加明显。肝硬化的类型及其炎症活动程度对睾丸大小无显著影响。然而，如果存在肝硬化肝脏的弥漫性脂肪浸润，则会表现出这种影响。在生物形态学方面，在生命的第4和第5个十年中观察到最大的平均睾丸大小。从第6个十年开始，睾丸大小在统计学上显著下降。酗酒组中平均睾丸大小值的曲线比对照组更平缓，且位于对照组下方。在这条曲线中睾丸大小值之间未发现统计学上的显著差异。肝硬化组的睾丸大小曲线低于这两条曲线，并且在第7和第9个十年之间发现了统计学上的显著差异。对照组、酗酒者和肝硬化患者的睾丸平均重量分别为17.58、16.49和13.25克，平均体积分别为16.37、15.34和12.21毫升，指数X的值分别为2.47、2.52和1.97，睾丸长度分别为5.05、4.08和3.61厘米，宽度分别为2.93、2.87和2.70厘米。
