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瑞士沃州的社会经济群体与癌症死亡风险

Socioeconomic groups and cancer risk at death in the Swiss Canton of Vaud.

作者信息

Levi F, Negri E, La Vecchia C, Te V C

机构信息

Vaud Cancer Registry, University Institute of Social and Preventive Medicine, CHUV, Lausanne.

出版信息

Int J Epidemiol. 1988 Dec;17(4):711-7. doi: 10.1093/ije/17.4.711.

Abstract

Data collected by the Cancer Registry of the Canton of Vaud, Switzerland, were used to estimate proportional mortality ratios (PMR) and mortality odds ratios (MOR) for various neoplasms according to social class and sector of occupation (agriculture versus others). Mortality ratios were elevated in lower social classes for cancers of the lung (MOR = 1.18 for social class IV or V vs I or II) and other sites strictly related to tobacco (mouth or pharynx, oesophagus and larynx; MOR = 1.70), and (though not significantly) for cancers of the stomach (MOR = 1.16) and uterus (MOR = 1.30 for cervix and 1.47 for corpus uteri). Furthermore, there was a strong negative social class gradient for thyroid cancer (a neoplasm with particularly elevated incidence and mortality in Switzerland), probably attributable to higher prevalence of iodine deficiency in lower social classes (MOR = 3.17). Positive social class gradients emerged for cancers of the intestines (MOR = 0.77 for social class IV or V), skin (MOR = 0.74) and prostate (MOR = 0.87). Agricultural workers showed decreased ratios for cancers of the lung (MOR = 0.75), cervix uteri (MOR = 0.72) and prostate (MOR = 0.80), and excess mortality from cancers of the upper digestive and respiratory sites (MOR = 1.22), stomach (MOR = 1.18), testis (MOR = 2.05) and lympho-haematopoietic neoplasms, particularly myeloma (MOR = 2.14).

摘要

瑞士沃州癌症登记处收集的数据用于估算不同肿瘤按社会阶层和职业部门(农业与其他部门)划分的比例死亡率(PMR)和死亡优势比(MOR)。社会阶层较低者的肺癌死亡率升高(IV或V级社会阶层与I或II级相比,MOR = 1.18),以及其他与烟草密切相关部位的癌症(口腔或咽部、食管和喉;MOR = 1.70),还有(虽无显著差异)胃癌(MOR = 1.16)和子宫癌(子宫颈MOR = 1.30,子宫体MOR = 1.47)。此外,甲状腺癌存在很强的社会阶层负梯度(瑞士发病率和死亡率特别高的一种肿瘤),可能归因于社会阶层较低者碘缺乏患病率较高(MOR = 3.17)。肠道癌(IV或V级社会阶层MOR = 0.77)、皮肤癌(MOR = 0.74)和前列腺癌(MOR = 0.87)出现了社会阶层正梯度。农业工人的肺癌(MOR = 0.75)、子宫颈癌(MOR = 0.72)和前列腺癌(MOR = 0.80)死亡率降低,而上消化道和呼吸道癌症(MOR = 1.22)、胃癌(MOR = 1.18)、睾丸癌(MOR = 2.05)以及淋巴造血系统肿瘤,尤其是骨髓瘤(MOR = 2.14)的死亡率过高。

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