Beghi E, Treviso M, Ferri P, Di Mascio R
Istituto di Ricerche Farmacologiche Mario Negri, Milano.
Ital J Neurol Sci. 1988 Dec;9(6):577-82. doi: 10.1007/BF02337012.
In the present study minimal clinical and electrophysiological criteria for the diagnosis of diabetic polyneuropathy (DP) have been tested in 48 unselected subjects attending an outpatient service for diabetics at the University Hospital of Chieti. A standard electrophysiological examination was performed in all patients on the median nerve (sensory and motor), peroneal nerve and sural nerve. Depending on the importance of the laboratory values for each nerve, nerve conduction velocity, distal latency and potential amplitude were given separate scores ranging from 0.5 to 2. A diagnosis of probable DP was made when abnormal findings were present in more than one nerve with a total score of 2.5 or more. As a whole, 28 cases (58%) had abnormal laboratory findings supporting the diagnosis of probable DP. There was a relatively high correlation between probable DP and a positive clinical examination although the validity coefficients of the neurological exam were not high enough to allow its use as a screening test for DP.
在本研究中，对基耶蒂大学医院糖尿病门诊的48名未经挑选的患者，测试了诊断糖尿病性多发性神经病变（DP）的最低临床和电生理标准。对所有患者的正中神经（感觉和运动）、腓总神经和腓肠神经进行了标准的电生理检查。根据每条神经实验室检查值的重要性，神经传导速度、远端潜伏期和电位幅度分别给予0.5至2分的评分。当一条以上神经出现异常结果且总分达到2.5分或更高时，诊断为可能的DP。总体而言，28例（58%）患者有异常实验室检查结果，支持可能的DP诊断。可能的DP与阳性临床检查之间存在较高的相关性，尽管神经学检查的效度系数不够高，不足以将其用作DP的筛查试验。
