Noël P
J Neurol Neurosurg Psychiatry. 1973 Oct;36(5):786-96. doi: 10.1136/jnnp.36.5.786.
In 59 diabetic patients, sensory nerve potentials were recorded at various sites along the course of the median nerve. Pathological responses were characterized by reduced amplitude, desynchronization and decreased conduction velocity (CV). Four groups of patients with increasingly severe nerve dysfunction were distinguished. The presence and severity of clinical neuropathy in the upper limbs could be related to decreased maximal sensory nerve CV in the proximal segment of the limbs. When maximal sensory nerve CV was normal above the wrist, neuropathy usually remained latent. In severe cases where no sensory nerve potentials could be recorded, the cerebral evoked potentials nonetheless permitted a precise evaluation of the somatosensory conduction. In these cases, maximal sensory nerve CV was very low. In five patients with a so-called diabetic mononeuropathy, abnormal nerve potentials were recorded in the median nerve, although no clinical signs could be seen in the corresponding territory. It is proposed that the diabetic nature of a mononeuropathy can be assessed by the finding of latent abnormalities in seemingly normal nerve.
在59例糖尿病患者中，沿正中神经走行的不同部位记录了感觉神经电位。病理反应的特征为波幅降低、去同步化和传导速度（CV）减慢。区分出了四组神经功能障碍日益严重的患者。上肢临床神经病变的存在及严重程度可能与肢体近端节段最大感觉神经CV降低有关。当腕部以上最大感觉神经CV正常时，神经病变通常仍处于潜伏状态。在严重到无法记录感觉神经电位的病例中，大脑诱发电位仍可对躯体感觉传导进行精确评估。在这些病例中，最大感觉神经CV非常低。在5例所谓的糖尿病性单神经病患者中，正中神经记录到了异常神经电位，尽管在相应区域未观察到临床体征。有人提出，单神经病的糖尿病性质可通过在看似正常的神经中发现潜伏性异常来评估。
