Chemical constituents of .

Phytochemical examination of Drake (Rutaceae), collected in Thailand, led to the isolation of seven coumarins, four furoquinolines, two amides, and one flavonoid glycoside. Four of these compounds, one coumarine derivative named as gravelliferone A (), two furoquinoline derivatives (kokusagenin A () and B ()) and one amide, clausenalansamide H (), are reported for the first time. Compound was isolated from the root bark, compound from the stem bark and compounds and from the leaves. The molecular structures of all isolated compounds were established by means of NMR experiments combined with mass spectrometry. Preliminary tests of the lipophilic stem bark extract against various human pathogenic bacteria strains revealed promising effects against ATCC 43300.