Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, China.
Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, China.
Anal Chim Acta. 2020 May 1;1109:130-139. doi: 10.1016/j.aca.2020.02.037. Epub 2020 Feb 21.
A novel three-dimensional nickel hydroxide/polyurethane (Ni(OH)/PU) electrode was prepared by a simple and environmentally friendly method and used for non-enzymatic detection of glucose. The Ni(OH)/PU electrode was obtained by one-pot hydrothermal method of loading nickel hydroxide on a cheap, easily available and flexible polyurethane sponge, which is facile and energy-saving. The porous structure of the polyurethane sponge provides a large surface area and a rich electrochemical active site for the electrode, which is beneficial to the oxidation reaction of glucose on the surface of the electrode with Ni(OH). The Ni(OH)/PU electrode structure was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The cyclic voltammetry test was used to study the catalytic performance of Ni(OH)/PU electrode for oxidation of glucose and the chronoamperometry was used to investigate the detection performance of Ni(OH)/PU electrode on glucose. The results indicate that this non-enzymatic glucose sensor had a high sensitivity of 2845 μA mM cm, a low detection limit of 0.32 μM (S/N = 3), a detection range of 0.01-2.06 mM and response time of less than 5 s. In addition, the Ni(OH)/PU electrode had excellent selectivity, reproducibility and stability and also exhibited effective detection of glucose in fetal bovine serum (FBS). In summary, Ni(OH)/PU electrode had broad prospects as an excellent candidate for non-enzymatic glucose sensors. The study also opens up a facile and energy-saving approach for preparing three-dimensional (3D) functionalized polymer electrode via hydrothermal method as electrochemical sensors.
一种新型的三维氢氧化镍/聚氨酯（Ni(OH)/PU）电极通过一种简单且环保的方法制备，并用于非酶葡萄糖检测。Ni(OH)/PU 电极是通过将氢氧化镍负载在廉价、易得且具有柔韧性的聚氨酯海绵上的一锅水热法获得的，该方法简单且节能。聚氨酯海绵的多孔结构为电极提供了较大的表面积和丰富的电化学活性位点，有利于 Ni(OH)表面上葡萄糖的氧化反应。通过扫描电子显微镜（SEM）、透射电子显微镜（TEM）、X 射线衍射（XRD）和 X 射线光电子能谱（XPS）对 Ni(OH)/PU 电极结构进行了表征。通过循环伏安法测试研究了 Ni(OH)/PU 电极对葡萄糖氧化的催化性能，通过计时电流法研究了 Ni(OH)/PU 电极对葡萄糖的检测性能。结果表明，该非酶葡萄糖传感器具有 2845 μA mM cm 的高灵敏度、0.32 μM（S/N = 3）的低检测限、0.01-2.06 mM 的检测范围和小于 5 s 的响应时间。此外，Ni(OH)/PU 电极具有出色的选择性、重现性和稳定性，并且在胎牛血清（FBS）中也能有效检测葡萄糖。总之，Ni(OH)/PU 电极作为非酶葡萄糖传感器具有广阔的前景。该研究还为通过水热法制备三维（3D）功能化聚合物电极作为电化学传感器开辟了一种简单且节能的方法。
