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淡漠与 HIV 疾病药物依从性的关键心理决定因素有关。

Apathy is Associated with Critical Psychological Determinants of Medication Adherence in HIV Disease.

机构信息

Department of Psychology, University of Houston, 126 Heyne Bldg, Suite 204, Houston, TX, 77004, USA.

School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.

出版信息

J Clin Psychol Med Settings. 2021 Jun;28(2):301-312. doi: 10.1007/s10880-020-09715-7.

Abstract

Apathy is common in HIV, separable from depression, and has been associated with non-adherence to antiretroviral therapy (ART). We examined the associations between apathy and critical psychological determinants of ART adherence, as per the information-motivation-behavioral model, in 85 persons living with HIV. Apathy was measured using a composite of the apathy subscale of the Frontal Systems Behavioral Scale and the vigor-activation scale of the Profile of Mood States. Independent of major depressive disorder, apathy was related at small-to-medium effect sizes with motivation to adhere and self-efficacy for health-related decision-making and medication management, but not with HIV knowledge or medication management skills. These findings suggest that apathy plays a unique role in several critical health adherence determinants and support the importance of assessment and management of apathy to maximize health outcomes among individuals with HIV disease.

摘要

淡漠是 HIV 常见的症状,与抑郁症可区分,且与不遵守抗逆转录病毒治疗(ART)相关。我们根据信息-动机-行为模型,在 85 名 HIV 感染者中,检查了淡漠与 ART 遵医行为的关键心理决定因素之间的关联。淡漠使用额叶系统行为量表的淡漠分量表和心境状态剖面图的活力-激活量表的组合来测量。不论是否存在重度抑郁症,淡漠与坚持治疗的动机以及与健康相关决策和药物管理的自我效能呈小到中等效应量相关,但与 HIV 知识或药物管理技能无关。这些发现表明,淡漠在几个关键健康遵医决定因素中发挥独特作用,并支持评估和管理淡漠的重要性,以最大限度地提高 HIV 感染者的健康结果。

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