• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中国江苏省母婴配对样本中通过新生儿 TSH 评估的碘缺乏症。

Iodine Deficiency as Assessed by Neonatal TSH in a Sample of Mother-and-Newborn Pairs in Jiangsu Province, China.

机构信息

Clinical Medical College, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China.

Department of Clinical Nutrition, Northern Jiangsu People's Hospital, Yangzhou, 225001, Jiangsu Province, China.

出版信息

Biol Trace Elem Res. 2021 Jan;199(1):70-75. doi: 10.1007/s12011-020-02135-6. Epub 2020 Apr 6.

DOI:10.1007/s12011-020-02135-6
PMID:32253700
Abstract

China has eliminated iodine deficiency disorders since 2011 via the implementation of universal salt iodisation. Following this, a new revised salt iodisation policy was introduced to reduce iodine content in table salt. Since maternal iodine deficiency can lead to cognitive impairment and cretinism in infants, the aim of our study was to assess if the iodine status of pregnant women and neonates was affected by the introduction of new salt iodisation policy. The medical records of the pregnant women and their neonates in the Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China, between January 2018 and May 2018 were reviewed and obtained. Our study included 374 mother-and-newborn pairs. Mean age of the participants was 28 ± 4 years. TSH, FT3 and FT4 of the participants remained within the reference range. The prevalence of thyroid dysfunction was 4.3%. The overall mean neonatal TSH, birth weight and prevalence of low birth weight (LBW) was 2.56 ± 1.59 mIU/L, 3348 ± 465 g and 2.4%, respectively. The prevalence of neonatal TSH values > 5 mIU/L was 8.3%, which suggested the emergence of mild iodine deficiency (i.e. 3.0-19.9%) in our province. In conclusion, although our study reported an improvement of iodine status to mild iodine deficiency in 2017, our pregnant women remained to be iodine deficient. We recommended an ongoing monitoring of iodine status and advocate for the routine iodine supplementation together with iodised salt in Chinese pregnant women.

摘要

中国自 2011 年实施普遍食盐碘化以来,已消除碘缺乏病。在此之后,推出了新的修订食盐碘化政策,以降低食盐中的碘含量。由于孕妇碘缺乏会导致婴儿认知障碍和克汀病,因此我们的研究旨在评估新的食盐碘化政策的实施是否会影响孕妇和新生儿的碘状况。我们回顾了 2018 年 1 月至 5 月期间江苏省扬州市苏北人民医院的孕妇及其新生儿的病历记录,共纳入 374 对母婴。参与者的平均年龄为 28 ± 4 岁。参与者的 TSH、FT3 和 FT4 仍在参考范围内。甲状腺功能障碍的患病率为 4.3%。新生儿 TSH、出生体重和低出生体重(LBW)的总体发生率分别为 2.56 ± 1.59 mIU/L、3348 ± 465 g 和 2.4%。新生儿 TSH 值>5 mIU/L 的患病率为 8.3%,这表明我省已出现轻度碘缺乏(即 3.0-19.9%)。总之,尽管我们的研究报告 2017 年碘状况有所改善,但孕妇仍存在碘缺乏。我们建议对碘状况进行持续监测,并提倡对中国孕妇进行常规碘补充和食用碘盐。

相似文献

1
Iodine Deficiency as Assessed by Neonatal TSH in a Sample of Mother-and-Newborn Pairs in Jiangsu Province, China.中国江苏省母婴配对样本中通过新生儿 TSH 评估的碘缺乏症。
Biol Trace Elem Res. 2021 Jan;199(1):70-75. doi: 10.1007/s12011-020-02135-6. Epub 2020 Apr 6.
2
Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency?2012年中国大陆实施新修订的全民食盐加碘(USI)后,利用新生儿促甲状腺激素(TSH)评估孕妇和新生儿的碘营养状况:碘缺乏会再次出现吗?
Int J Endocrinol. 2019 Oct 7;2019:3618169. doi: 10.1155/2019/3618169. eCollection 2019.
3
Effect of maternal and neonatal factors on neonatal thyroid stimulating hormone: Results from a population-based prospective cohort study in China.母儿因素对新生儿促甲状腺激素的影响:来自中国基于人群的前瞻性队列研究的结果。
J Trace Elem Med Biol. 2018 Sep;49:151-156. doi: 10.1016/j.jtemb.2018.05.008. Epub 2018 May 25.
4
Iodine status remains critical in mother and infant in Central Anatolia (Kayseri) of Turkey.在土耳其安纳托利亚中部(开塞利),母婴的碘营养状况仍然至关重要。
Eur J Nutr. 2004 Oct;43(5):297-303. doi: 10.1007/s00394-004-0474-2. Epub 2004 Jan 30.
5
Thyroid function in the newborn in relation to maternal thyroid status during labour in a mild iodine deficiency endemic area in Sudan.苏丹轻度碘缺乏流行地区新生儿甲状腺功能与分娩时母亲甲状腺状态的关系
Clin Endocrinol (Oxf). 2001 Oct;55(4):485-90. doi: 10.1046/j.1365-2265.2001.01368.x.
6
Thyroid Function Reference Values in Healthy Iodine-Sufficient Pregnant Women and Influence of Thyroid Nodules on Thyrotropin and Free Thyroxine Values.健康碘充足孕妇的甲状腺功能参考值及甲状腺结节对促甲状腺激素和游离甲状腺素值的影响。
Thyroid. 2019 Mar;29(3):421-429. doi: 10.1089/thy.2018.0324. Epub 2019 Feb 22.
7
Neonatal thyroid function born to mothers living with long-term excessive iodine intake from drinking water.母亲长期通过饮水摄入过量碘所生育新生儿的甲状腺功能
Clin Endocrinol (Oxf). 2015 Sep;83(3):399-404. doi: 10.1111/cen.12625. Epub 2014 Nov 5.
8
Geographical influences on the iodine status in pregnant women, neonates, and school-age children in China.地理因素对中国孕妇、新生儿及学龄儿童碘营养状况的影响。
Nutr J. 2020 Jan 21;19(1):7. doi: 10.1186/s12937-020-0525-4.
9
Neonatal TSH as a marker of iodine nutrition status. Effect of maternal ioduria and thyroid function on neonatal TSH.新生儿促甲状腺激素作为碘营养状况的标志物。孕妇尿碘和甲状腺功能对新生儿促甲状腺激素的影响。
An Pediatr (Engl Ed). 2022 Dec;97(6):375-382. doi: 10.1016/j.anpede.2022.09.008. Epub 2022 Oct 11.
10
Assessment of thyroid function in children, adults and pregnant and lactating women after long-term salt iodisation measurements.长期盐碘化测量后儿童、成人和孕妇及哺乳期妇女甲状腺功能评估。
Br J Nutr. 2018 Jun;119(11):1245-1253. doi: 10.1017/S0007114518000570. Epub 2018 Mar 27.

引用本文的文献

1
Maternal iron deficiency assessed by serum ferritin and birth outcomes in mainland China.中国大陆地区通过血清铁蛋白评估的孕产妇缺铁情况与分娩结局
Sci Rep. 2025 Jan 7;15(1):1098. doi: 10.1038/s41598-024-80852-x.
2
Pregnant women at risk for iodine deficiency but adequate iodine intake in school-aged children of Zhejiang Province, China.中国浙江省碘摄入充足但存在碘缺乏风险的孕妇和学龄儿童。
Environ Geochem Health. 2024 May 2;46(6):204. doi: 10.1007/s10653-024-01934-3.
3
Editorial: Nutrient requirements and diabetes during pregnancy.

本文引用的文献

1
Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency?2012年中国大陆实施新修订的全民食盐加碘(USI)后,利用新生儿促甲状腺激素(TSH)评估孕妇和新生儿的碘营养状况:碘缺乏会再次出现吗?
Int J Endocrinol. 2019 Oct 7;2019:3618169. doi: 10.1155/2019/3618169. eCollection 2019.
2
Iodine status of 8 to 10 years old children within 20 years following compulsory salt iodization policy in Shanghai, China.中国上海实施食盐强制碘化政策 20 年后 8 至 10 岁儿童碘营养状况
Nutr J. 2019 Nov 2;18(1):63. doi: 10.1186/s12937-019-0491-x.
3
社论:孕期营养需求与糖尿病
Front Nutr. 2023 Oct 25;10:1270576. doi: 10.3389/fnut.2023.1270576. eCollection 2023.
4
Iodine nutrition status and thyroid autoimmunity during pregnancy: a cross-sectional study of 4635 pregnant women.孕期碘营养状况与甲状腺自身免疫:4635 例孕妇的横断面研究。
Nutr J. 2022 Jan 29;21(1):7. doi: 10.1186/s12937-022-00760-6.
5
The Results of 16 Years Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey.16年碘盐加碘的结果:土耳其安塔利亚学龄儿童碘缺乏状况评估
J Clin Res Pediatr Endocrinol. 2020 Sep 2;12(3):329-330. doi: 10.4274/jcrpe.galenos.2019.2019.0036. Epub 2020 Mar 11.
Iodine Nutrition and Thyroid Function in Pregnant Women Exposed to Different Iodine Sources.
暴露于不同碘源的孕妇的碘营养状况与甲状腺功能
Biol Trace Elem Res. 2020 Feb;193(2):574-575. doi: 10.1007/s12011-019-01719-1. Epub 2019 Apr 16.
4
A Review of Iodine Status of Women of Reproductive Age in the USA.美国育龄妇女碘营养状况综述
Biol Trace Elem Res. 2019 Mar;188(1):208-220. doi: 10.1007/s12011-018-1606-5. Epub 2019 Jan 7.
5
Pre-analytical Factors Influence Accuracy of Urine Spot Iodine Assessment in Epidemiological Surveys.分析前因素影响流行病学调查中尿碘点评估的准确性。
Biol Trace Elem Res. 2019 Jul;190(1):281. doi: 10.1007/s12011-018-1512-x. Epub 2018 Sep 12.
6
Assessment of thyroid function in children, adults and pregnant and lactating women after long-term salt iodisation measurements.长期食盐加碘测量后儿童、成人以及孕妇和哺乳期妇女的甲状腺功能评估。
Br J Nutr. 2018 Oct;120(7):839-840. doi: 10.1017/S0007114518002003. Epub 2018 Aug 30.
7
A Comparative Study of Iodized Salt Programs: Shanghai and Switzerland.碘盐项目的比较研究:上海与瑞士
Biol Trace Elem Res. 2019 Jun;189(2):586. doi: 10.1007/s12011-018-1478-8. Epub 2018 Aug 14.
8
Iodine deficiency in pregnant women after the adoption of the new provincial standard for salt iodization in Zhejiang Province, China.中国浙江省采用新的食盐碘化省级标准后孕妇碘缺乏。
BMC Pregnancy Childbirth. 2018 Aug 3;18(1):313. doi: 10.1186/s12884-018-1952-5.
9
Iodine Deficiency in Zhejiang Pregnant Women in the Context of Universal Salt Iodization Programme.全民食盐碘化背景下浙江孕妇碘缺乏状况
Sci Rep. 2018 Jun 11;8(1):8835. doi: 10.1038/s41598-018-26942-z.
10
The Reference Intervals of Thyroid Hormones for Pregnant Women in Zhejiang Province.浙江省孕妇甲状腺激素参考区间
Lab Med. 2017 Dec 22;49(1):5-10. doi: 10.1093/labmed/lmx070.