School of Pharmacy, The University of Queensland, Brisbane, Australia.
Sydney Pharmacy School, The University of Sydney, Sydney, Australia.
Clin Exp Optom. 2021 Apr;104(3):406-411. doi: 10.1111/cxo.13066. Epub 2021 Mar 23.
Compounded ophthalmic products can be helpful for a small number of patients who cannot use a commercially available product or for whom no commercially available product exists. Extemporaneous preparation of medicines for the eye is considered complex compounding and is best undertaken by pharmacists with the appropriate facilities and equipment to ensure a sterile product. When dispensing, the pharmacist evaluates medication appropriateness, effectiveness and safety for each individual patient. For a compounded medicine, the pharmacist will also pay close attention to the formulation, physical, chemical and microbiological stability and utility of the preparation. Optometrists who are considering writing a prescription for any medicine will find that the pharmacist is a useful source of information regarding the availability of alternatives, stock outages and the availability or feasibility of a compounded product. Compounding can be a useful adjunct to the care of some patients and patient safety should always be paramount.
配制的眼科产品对一小部分不能使用市售产品或不存在市售产品的患者可能有帮助。为眼睛临时配制药物被认为是复杂的配制，最好由具备适当设施和设备的药剂师来进行，以确保产品无菌。配药时，药剂师会根据每位患者的具体情况评估药物的适用性、有效性和安全性。对于配制药物，药剂师还会密切关注制剂的配方、物理、化学和微生物稳定性以及实用性。考虑为任何药物开处方的验光师会发现，药剂师是一个有用的信息来源，可了解替代药物的可用性、库存短缺情况以及配制产品的可用性或可行性。对于某些患者来说，配制可能是一种有用的辅助治疗方法，而患者安全始终应是重中之重。
