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轮状病毒脑炎合并急性小脑炎:病例报告及文献复习。

Rotavirus encephalopathy with concomitant acute cerebellitis: report of a case and review of the literature.

机构信息

Divisions of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.

Pediatric Radiology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.

出版信息

Turk J Pediatr. 2020;62(1):119-124. doi: 10.24953/turkjped.2020.01.017.

Abstract

Rotavirus is a leading cause of gastroenteritis in children under 5 years of age. It is known that neurological manifestations like seizures, encephalopathy and encephalitis can rarely be seen due to rotavirus infections. Cerebellar involvement is extremely rare. We present an uncommon neurological manifestation of rotavirus infection in a 4-year-old Turkish child who presented with hypotonia, reduced consciousness and mutism. Magnetic resonance imaging revealed diffusion abnormalities in the splenium of corpus callosum and nucleus dentatus bilaterally. She was diagnosed with rotavirus cerebellitis. She improved well with dexamethasone and intravenous immunoglobulin but still has dysarthria and poor fine motor coordination.

摘要

轮状病毒是导致 5 岁以下儿童患肠胃炎的主要原因。已知轮状病毒感染偶尔会引起神经系统表现,如癫痫发作、脑病和脑炎。小脑受累极为罕见。我们报告了一例 4 岁土耳其儿童感染轮状病毒的罕见神经系统表现,该患儿表现为肌张力减退、意识减退和缄默。磁共振成像显示胼胝体压部和双侧齿状核弥散异常。诊断为轮状病毒小脑炎。她使用地塞米松和静脉注射免疫球蛋白后病情明显好转,但仍存在构音障碍和精细运动协调不良。

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