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非肿瘤手术病因小脑缄默症综合征:病例报告及文献复习。

Cerebellar mutism syndrome of non-tumour surgical aetiology-a case report and literature review.

机构信息

Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

出版信息

Childs Nerv Syst. 2023 Aug;39(8):2201-2213. doi: 10.1007/s00381-023-05947-8. Epub 2023 May 4.

Abstract

Cerebellar mutism syndrome (CMS) is a well-known complication of posterior fossa (PF) tumour surgery. CMS has previously been reported in cases of non-tumour surgical aetiology in a limited number of publications. We report a case of a 10-year-old girl who suffered a cerebellar haemorrhage and subsequent CMS following surgical treatment of a ruptured arteriovenous malformation (AVM) in the cerebellar vermis. The AVM was removed acutely through a transvermian access, and hydrocephalus was treated with temporary external drainage. In the postoperative period, she suffered diffuse vasospasms of the anterior cerebral circulation and had a permanent shunt placed for hydrocephalus. Her mutism resolved after 45 days but severe ataxia persisted. To our knowledge, this is the first reported case of CMS related to a vermian haemorrhagic stroke with postoperative diffuse vasospasms. Based on this case, we present a literature review on CMS of non-tumour surgical origin in children.

摘要

小脑缄默症(CMS)是后颅窝(PF)肿瘤手术的一种已知并发症。CMS 以前曾在少数出版物中报道过非肿瘤手术病因的病例。我们报告了一例 10 岁女孩的病例,她在小脑蚓部动静脉畸形(AVM)破裂后接受手术治疗,随后出现小脑出血和随后的 CMS。AVM 通过经蚓部入路急性切除,并通过临时外部引流治疗脑积水。在术后期间,她患有前脑循环的弥漫性血管痉挛,并因脑积水放置了永久性分流管。她的缄默症在 45 天后得到缓解,但严重的共济失调仍持续存在。据我们所知,这是首例与术后弥漫性血管痉挛相关的小脑出血性中风并发 CMS 的报道。基于此病例,我们对儿童非肿瘤手术源性 CMS 进行了文献复习。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/472b/10390373/4a4b9ac0710f/381_2023_5947_Fig1_HTML.jpg

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