ACE2 两面蛋白——从心血管保护到严重急性呼吸综合征冠状病毒 2 和 COVID-19。
ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.
机构信息
Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, U.K.
Department of Cardiology, Renmin Hopsital of Wuhan University, Institute of Model Animal of Wuhan University, Wuhan, China.
出版信息
Clin Sci (Lond). 2020 Apr 17;134(7):747-750. doi: 10.1042/CS20200363.
Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.
血管紧张素转换酶 2（ACE2）是将血管紧张素 II 转化为血管紧张素-(1-7)的主要酶。它也是严重急性呼吸系统综合征（SARS）-冠状病毒（CoV）-2 的受体，后者引发冠状病毒病（COVID-19）。鉴于 ACE2 的重要性，并为庆祝其发现 20 周年，该杂志将出版一期专刊，重点介绍这种多功能蛋白的基础科学和（病理）生理学作用。
Zotero 插件