Dong Xiaojuan, Wang Ruige, Jin Weiwei, Liu Chenjiang
The Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, Urumqi Key Laboratory of Green Catalysis and Synthesis Technology, School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, P.R. China.
Org Lett. 2020 Apr 17;22(8):3062-3066. doi: 10.1021/acs.orglett.0c00814. Epub 2020 Apr 7.
We report a direct and green electrochemical oxidative cross-dehydrogenative coupling reaction of -heterocycles with hydrogen phosphoryl compounds under external oxidant-free conditions. Various phosphorylation products of substituted carbazoles and indoles are assembled in modest to excellent yields. A hydrogen release process is preliminarily demonstrated and H is the sole byproduct. An imidazolium based ionic liquid is selected as the optimal electrolyte.
我们报道了在无外部氧化剂条件下，-杂环与氢磷酰化合物的直接绿色电化学氧化交叉脱氢偶联反应。取代咔唑和吲哚的各种磷酸化产物以中等至优异的产率得到。初步证明了氢释放过程，且H是唯一的副产物。选择了一种基于咪唑鎓的离子液体作为最佳电解质。
