Department of Respiratory Medicine, Beijing Jishuitan Hospital, Beijing, People's Republic of China.
Clinical Epidemiology Research Center, Beijing Jishuitan Hospital, Beijing, People's Republic of China.
Clin Interv Aging. 2020 Mar 19;15:419-424. doi: 10.2147/CIA.S241592. eCollection 2020.
Pneumonia is a serious complication following hip fracture and is the primary risk factor for 30-day mortality after surgery. Modifying several laboratory factors may improve the outcomes of fragile hip fracture patients who are 80 years or older.
To investigate several adjustable factors for perioperative pneumonia in order to improve patient prognosis and reduce mortality.
We retrospectively reviewed in-hospital hip fracture data from patients who were 80 years or over between January 1, 2014, and November 31, 2014, from Beijing Jishuitan Hospital. Patients were divided into two groups: perioperative pneumonia (POP) group and non-perioperative pneumonia (non-POP) group. Logistic regression models were used to identify independent risk factors. Statistical significance was set at 5% (p<0.05).
The incidence of perioperative pneumonia (POP) in patients 80 years and older was 11.3% (33/293). Male patients had a higher incidence of POP (20/96 cases, 20.83%) compared to females (13/197, 6.6%)(P<0.001). Higher neutrophilic granulocyte percentages (78.148%±9.162% in POP vs 81.959%±6.142% in Non-POP, P=0.033) and lower albumin levels (χ=2.25, P=0.039) were observed in the POP group at baseline. After multivariate logistic regression, we observed that males (OR=3.402, P=0.048), lower albumin levels (OR=10.16, P=0.001) and PaO2 levels (OR=2.916, P=0.007) were independent risk factors for POP.
Low albumin and oxygen levels and the male gender were risk factors for perioperative pneumonia in geriatric hip fracture patients.
肺炎是髋部骨折后的严重并发症,也是手术后 30 天内死亡的主要危险因素。改变几个实验室因素可能会改善 80 岁及以上脆弱性髋部骨折患者的预后并降低死亡率。
研究围手术期肺炎的几个可调节因素,以改善患者的预后并降低死亡率。
我们回顾性分析了 2014 年 1 月 1 日至 2014 年 11 月 31 日期间北京积水潭医院 80 岁及以上的住院髋部骨折患者的数据。患者分为两组:围手术期肺炎(POP)组和非围手术期肺炎(非-POP)组。使用逻辑回归模型确定独立危险因素。统计学意义设为 5%(p<0.05)。
80 岁及以上患者围手术期肺炎(POP)的发生率为 11.3%(33/293)。男性患者的 POP 发生率(20/96 例,20.83%)高于女性(13/197 例,6.6%)(P<0.001)。POP 组的中性粒细胞百分比(78.148%±9.162%)高于非-POP 组(81.959%±6.142%)(P=0.033),白蛋白水平较低(χ=2.25,P=0.039)。多变量逻辑回归后,我们观察到男性(OR=3.402,P=0.048)、低白蛋白水平(OR=10.16,P=0.001)和 PaO2 水平(OR=2.916,P=0.007)是 POP 的独立危险因素。
低白蛋白和氧水平以及男性是老年髋部骨折患者围手术期肺炎的危险因素。