Cao Weiping, Ni Xia, Wang Qin, Li Jie, Li Yan, Chen Tingmei, Wang Xinzhi
Department of Obstetrics, Maternity and Child Health Hospital of Zhenjiang, Zhenjiang, Jiangsu 212001, P.R. China.
Department of Imaging, Maternity and Child Health Hospital of Zhenjiang, Zhenjiang, Jiangsu 212001, P.R. China.
Exp Ther Med. 2020 Apr;19(4):2923-2926. doi: 10.3892/etm.2020.8548. Epub 2020 Feb 25.
Ovarian vein thrombosis (OVT) is a rare medical complication that is most often diagnosed in the post-partum period. OVT can lead to conditions, including sepsis, inferior vena cava (IVC), pulmonary emboli and mortality. The current study outlines a case of a patient who experienced pain in the lower abdomen and waist without fever postpartum following caesarean section (CS). Plasma FDP, D-Dimer and fibrinogen levels were markedly increased following CS and this was an indicator of the rapid progression of blood coagulation and fibrinolysis. Increased maternal lipid may be one of the risk factors for thrombosis. Based on the clinical presentation, a CT scan demonstrated thrombosis of the right ovarian vein and inferior vena cava, and a diagnosis of OVT and IVC thrombosis was subsequently made. In the current case, an anticoagulant therapy was started with a subcutaneous injection low molecular weight heparin calcium, an intravenous urokinase drip as a thrombolytic agent and implantation of inferior vena cava filters as a novel method of treatment for thrombosis. The patient was discharged from hospital 20 days following treatment in a good condition. The current study reports a case of OVT associated with IVC that was successfully managed without complication.
卵巢静脉血栓形成(OVT)是一种罕见的医学并发症,最常在产后被诊断出来。OVT可导致包括败血症、下腔静脉(IVC)、肺栓塞和死亡等情况。本研究概述了一例剖宫产(CS)术后产后无发热但出现下腹部和腰部疼痛的患者病例。剖宫产术后血浆纤维蛋白降解产物(FDP)、D-二聚体和纤维蛋白原水平显著升高,这是凝血和纤溶快速进展的一个指标。母体血脂升高可能是血栓形成的危险因素之一。根据临床表现,CT扫描显示右卵巢静脉和下腔静脉血栓形成,随后诊断为OVT和IVC血栓形成。在本病例中,开始采用皮下注射低分子肝素钙进行抗凝治疗,静脉滴注尿激酶作为溶栓剂,并植入下腔静脉滤器作为一种新的血栓治疗方法。患者在治疗20天后康复出院,状况良好。本研究报告了一例与IVC相关的OVT病例,该病例成功得到处理,无并发症发生。