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加拿大医疗环境下骨折联络服务的评估

Evaluation of the Fracture Liaison Service within the Canadian Healthcare Setting.

作者信息

Wong-Pack Matthew, Naqvi Nawazish, Ioannidis George, Khalil Ramy, Papaioannou Alexandra, Adachi Jonathan, Lau Arthur N

机构信息

Department of Medicine, University of Toronto, Toronto, ON, Canada.

Division of Rheumatology, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.

出版信息

J Osteoporos. 2020 Mar 21;2020:6742604. doi: 10.1155/2020/6742604. eCollection 2020.

Abstract

Previous studies evaluating fracture liaison service (FLS) programs have found them to be cost-effective, efficient, and reduce the risk of fracture. However, few studies have evaluated the clinical effectiveness of these programs. We compared the patient populations of those referred for osteoporosis management by FLS to those referred by primary care physicians (PCP), within the Canadian healthcare system in the province of Ontario. Specifically, we investigated if a referral from FLS is similarly effective as PCP at identifying patients at risk for future osteoporotic fractures and if osteoporosis therapies have been previously initiated. A retrospective chart review of patients assessed by a single Ontario rheumatology practice affiliated with FLS between January 1, 2014, and December 31, 2017, was performed identifying two groups: those referred by FLS within Hamilton and those referred by their PCP for osteoporosis management. Fracture risk of each patient was determined using FRAX. A total of 573 patients ( = 225 (FLS group) and  = 227 (PCP group)) were evaluated. Between the FLS and PCP groups, there were no significant differences in the absolute 10-year risk of a major osteoporotic fracture (15.6% (SD = 10.2) vs 15.3% (SD = 10.3)) and 10-year risk of hip fracture (4.7% (SD = 8.3) vs 4.7% (SD = 6.8)), respectively. 10.7% of patients referred by FLS and 40.5% of patients referred by their PCP were on osteoporosis medication prior to fracture. Our study suggests that referral from FLS is similarly effective as PCP at identifying patients at risk for future osteoporotic fractures, and clinically effective at identifying the care gap with the previous use of targeted osteoporosis therapies from referral from PCP being low and much lower in those referred by FLS. Interventional programs such as FLS can help close the treatment gap by providing appropriate care to patients that were not previously identified to be at risk for fracture by their primary care physician and initiate proper medical management.

摘要

以往评估骨折联络服务(FLS)项目的研究发现,这些项目具有成本效益、效率高且能降低骨折风险。然而,很少有研究评估这些项目的临床效果。我们在加拿大安大略省的医疗系统内,比较了通过FLS转诊进行骨质疏松症管理的患者群体与由初级保健医生(PCP)转诊的患者群体。具体而言,我们调查了FLS的转诊在识别未来有骨质疏松性骨折风险的患者方面是否与PCP同样有效,以及之前是否已启动骨质疏松症治疗。对2014年1月1日至2017年12月31日期间由与FLS相关的安大略省单一风湿病诊所评估的患者进行了回顾性病历审查,确定了两组:汉密尔顿市内由FLS转诊的患者和由其PCP转诊进行骨质疏松症管理的患者。使用FRAX确定每位患者的骨折风险。总共评估了573名患者(=225名(FLS组)和=227名(PCP组))。在FLS组和PCP组之间,主要骨质疏松性骨折的绝对10年风险(15.6%(标准差=10.2)对15.3%(标准差=10.3))和髋部骨折的10年风险(4.7%(标准差=8.3)对4.7%(标准差=6.8))分别无显著差异。FLS转诊的患者中有10.7%以及PCP转诊的患者中有40.5%在骨折前正在接受骨质疏松症药物治疗。我们的研究表明,FLS的转诊在识别未来有骨质疏松性骨折风险的患者方面与PCP同样有效,并且在识别护理差距方面具有临床效果,因为PCP转诊患者之前使用靶向骨质疏松症治疗的比例较低,而FLS转诊患者的这一比例更低。像FLS这样的干预项目可以通过为那些之前未被其初级保健医生识别为有骨折风险的患者提供适当护理并启动适当的医疗管理,来帮助缩小治疗差距。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ab0/7115141/f982c9e749e0/JOS2020-6742604.001.jpg

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