Hou G L, Tsai C C
Department of Periodontics, School of Dentistry, Kaohsiung Medical College, Taiwan, R.O.C.
J Periodontol. 1988 Dec;59(12):852-5. doi: 10.1902/jop.1988.59.12.852.
A 25-YEAR-OLD CHINESE FEMALE, five months pregnant, came to our dental clinic with a chief complaint of slight gingival inflammation. A diagnosis of pregnancy gingivitis was made. One week later, there was a sudden onset of extremely generalized gingival enlargement and very high WBC count (144,000/cmm) was noted. Physical, laboratory, and microscopic examination led to the diagnosis of acute myelomonocytic leukemia. The observations of good oral hygiene and clinical course suggested that leukemic cell infiltration was the major cause of sudden onset of gingival enlargement. This article emphasizes the importance of primary gingival enlargement in the initial diagnosis of leukemia.
一名25岁的中国女性，怀孕5个月，因轻微牙龈炎症为主诉前来我们的牙科诊所。诊断为妊娠性龈炎。一周后，突然出现极其广泛的牙龈肿大，并且发现白细胞计数非常高（144,000/立方毫米）。体格检查、实验室检查和显微镜检查确诊为急性粒单核细胞白血病。良好的口腔卫生状况及临床病程观察表明，白血病细胞浸润是牙龈突然肿大的主要原因。本文强调原发性牙龈肿大在白血病初步诊断中的重要性。
