Lim Hyun-Chang, Kim Chang-Sung
Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea.
Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea. ; Department of Applied Life Science, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Korea.
J Periodontal Implant Sci. 2014 Dec;44(6):293-9. doi: 10.5051/jpis.2014.44.6.293. Epub 2014 Dec 31.
Systemic disease can manifest oral signs at an early phase, which may be crucial for the diagnosis and timing of treatment. This report describes two patients who presented with gingival enlargement as an early sign of acute leukemia.
Two patients presented with oral symptoms including severe gingival enlargement. The progress of their symptoms was associated with underlying systemic disease.
The patients were transferred to the Department of Hematology and diagnosed with acute myelomonocytic leukemia. They received appropriate treatment and survived.
Gingival enlargement can be caused by underlying systemic diseases. Accurate diagnosis and timely referral are important for preventing a fatal situation. It must be emphasized that some oral signs and symptoms may be closely correlated with systemic diseases.
全身性疾病可在早期出现口腔症状，这对于诊断和治疗时机可能至关重要。本报告描述了两名以牙龈肿大作为急性白血病早期症状的患者。
两名患者出现包括严重牙龈肿大在内的口腔症状。其症状进展与潜在的全身性疾病相关。
患者被转至血液科，诊断为急性粒单核细胞白血病。他们接受了适当治疗并存活下来。
牙龈肿大可能由潜在的全身性疾病引起。准确诊断和及时转诊对于预防致命情况很重要。必须强调的是，一些口腔症状可能与全身性疾病密切相关。
