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一例非典型淋巴细胞性小叶性脂膜炎

A Case of Atypical Lymphocytic Lobular Panniculitis.

作者信息

Ni Catherine S, Sarantopoulos G Peter, Chiu Melvin

机构信息

Dermatology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, USA.

Pathology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, USA.

出版信息

Cureus. 2020 Feb 28;12(2):e7134. doi: 10.7759/cureus.7134.

Abstract

Atypical lymphocytic lobular panniculitis (ALLP) is a rare T-cell dyscrasia of the subcutaneous fat. It typically presents with indurated erythematous nodules on the lower extremities and often will have a relapsing and remitting course. The cause is unknown, but clinically and histopathologically it shares similarities to lupus panniculitis (LP) and subcutaneous panniculitis-like T-cell lymphoma (SPTCL). It generally has an indolent course, and may best be treated like indolent versions of SPTCL with systemic steroids and immunosuppressive medications.

摘要

非典型淋巴细胞性小叶性脂膜炎(ALLP)是一种罕见的皮下脂肪T细胞异常增殖性疾病。其典型表现为下肢出现硬结性红斑结节,且病程常呈复发缓解型。病因不明,但在临床和组织病理学上与狼疮性脂膜炎(LP)及皮下脂膜炎样T细胞淋巴瘤(SPTCL)有相似之处。它通常病程进展缓慢,或许采用全身性类固醇和免疫抑制药物治疗,效果最佳,就如同治疗病情进展缓慢的SPTCL一样。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acf3/7105265/b6d9b23559aa/cureus-0012-00000007134-i01.jpg

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