Nelson R W, Stookey L J, Kazacos E
Department of Small Animal Clinics, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907.
J Vet Intern Med. 1988 Jul-Sep;2(3):133-7. doi: 10.1111/j.1939-1676.1988.tb02809.x.
Idiopathic chronic colitis was diagnosed in 13 dogs. Owners sought veterinary care because of semiformed to liquid feces, fresh blood and/or mucus in the feces, tenesmus, increased frequency of defecation, vomiting, weight loss, and flatulence in their dogs. A lymphocytic, plasmacytic infiltration in the colonic lamina propria was found on colonic biopsy specimens. Signs resolved in all 13 dogs after they were fed a low residue, easily assimilated, relatively hypoallergenic diet. In 11 dogs, two commercial diets not previously fed to these dogs were successfully substituted for the initial test diet, without causing recurrence of signs. Only two of these 11 dogs subsequently tolerated a switch to diets that had been fed at the time of onset of signs of colitis. All 13 dogs have been successfully managed from 2 months to 28 months following the initiation of dietary therapy. The results of these dietary challenges strongly suggest a dietary role in the pathogenesis of this disorder, and also illustrate the importance of dietary therapy in the management of idiopathic chronic colitis.
13只犬被诊断为特发性慢性结肠炎。由于犬出现软便至稀便、粪便中有鲜血和/或黏液、里急后重、排便频率增加、呕吐、体重减轻以及肠胃胀气等症状，犬主们寻求兽医治疗。对结肠活检标本进行检查时，发现结肠固有层有淋巴细胞和浆细胞浸润。在给这13只犬喂食低残渣、易消化、相对低敏的日粮后，所有犬的症状均得到缓解。在11只犬中，两种之前未喂食过的市售日粮成功替代了初始试验日粮，且未导致症状复发。这11只犬中只有两只随后能够耐受换成结肠炎症状出现时所喂食的日粮。自开始饮食治疗后的2个月至28个月，所有13只犬均得到成功管理。这些饮食激发试验的结果有力地表明饮食在该疾病发病机制中起作用，同时也说明了饮食治疗在特发性慢性结肠炎管理中的重要性。
