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肺腺性乳头状瘤的诊断与治疗:一例报告

Diagnosis and management of glandular papilloma of lung: A case report.

作者信息

Wu Chien-Wei, Chen Ann, Huang Tsai-Wang

机构信息

Department of Surgery, Tri-Service General Hospital, Taipei 114, Taiwan.

Department of Pathology, Tri-Service General Hospital, Taipei 114, Taiwan.

出版信息

World J Clin Cases. 2020 Mar 26;8(6):1104-1107. doi: 10.12998/wjcc.v8.i6.1104.

DOI:10.12998/wjcc.v8.i6.1104
PMID:32258080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7103975/
Abstract

BACKGROUND

Solitary respiratory papilloma is a rare epithelial tumor that can be categorized into multiple subtypes depending on tumor location, histological presentation and number. The glandular type is the rarest, with only 30 cases available within the field. Hence, information on its identification and treatment is limited. In this report, we discuss the diagnostic strategy and management of glandular papilloma, along with a review of the literature.

CASE SUMMARY

We describe a male 44-year-old nonsmoker who presented with a persistent cough and recurrent pneumonia, which he had experienced for over 2 years. A solitary pulmonary nodule with an endobronchial lesion was found computed tomography of the chest. After a biopsy was obtained, no definite diagnosis could be made. Glandular papilloma of the lung was confirmed video-assisted thoracoscopic anatomic resection of the right lower lobe of the lung. The patient remained disease-free after 6 mo follow up.

CONCLUSION

Minimally invasive surgery is feasible for the surgical resection of endobronchial glandular papilloma. Although rare, glandular papilloma should be considered in patients with infection or endobronchial lesions.

摘要

背景

孤立性呼吸道乳头状瘤是一种罕见的上皮性肿瘤,可根据肿瘤位置、组织学表现和数量分为多种亚型。腺型是最罕见的,该领域仅有30例病例。因此,关于其识别和治疗的信息有限。在本报告中,我们讨论腺型乳头状瘤的诊断策略和管理,并对文献进行综述。

病例摘要

我们描述了一名44岁不吸烟男性,他出现持续咳嗽和反复肺炎,症状持续超过2年。胸部计算机断层扫描发现一个伴有支气管内病变的孤立性肺结节。活检后未能做出明确诊断。通过电视辅助胸腔镜对右下肺叶进行解剖切除,确诊为肺腺型乳头状瘤。随访6个月后,患者无疾病复发。

结论

微创手术对于支气管内腺型乳头状瘤的手术切除是可行的。尽管罕见,但对于有感染或支气管内病变的患者应考虑腺型乳头状瘤的可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca6/7103975/64083056a257/WJCC-8-1104-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca6/7103975/ede17c86f3ee/WJCC-8-1104-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca6/7103975/64083056a257/WJCC-8-1104-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca6/7103975/ede17c86f3ee/WJCC-8-1104-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca6/7103975/64083056a257/WJCC-8-1104-g002.jpg

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引用本文的文献

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Glandular papilloma in lung parenchyma.肺实质内的腺性乳头状瘤。
Respirol Case Rep. 2024 May 21;12(5):e01389. doi: 10.1002/rcr2.1389. eCollection 2024 May.

本文引用的文献

1
Respiratory papillomas.呼吸道乳头状瘤
Lung India. 2016 Sep-Oct;33(5):522-7. doi: 10.4103/0970-2113.188973.
2
Rapidly growing glandular papilloma associated with mucus production: a case report.与黏液分泌相关的快速生长腺性乳头状瘤:一例报告
World J Surg Oncol. 2014 May 22;12:160. doi: 10.1186/1477-7819-12-160.
3
Solitary peripheral pulmonary papilloma evaluation on frozen section: a potential pitfall for the pathologist.孤立性肺外周乳头状瘤的冰冻切片评估:病理医生的潜在陷阱。
Pathol Res Pract. 2012 Dec 15;208(12):726-9. doi: 10.1016/j.prp.2012.09.007. Epub 2012 Nov 3.
4
Solitary papillomas of the lower airways: epidemiological, clinical, and therapeutic data during a 22-year period and review of the literature.下呼吸道孤立性乳头状瘤:22 年期间的流行病学、临床和治疗数据及文献复习。
J Thorac Oncol. 2012 Apr;7(4):643-8. doi: 10.1097/JTO.0b013e3182468d06.