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小学室内空气质量与特应性致敏:一项随访研究。

Indoor air quality and atopic sensitization in primary schools: A follow-up study.

作者信息

Rufo João Cavaleiro, Madureira Joana, Paciência Inês, Aguiar Lívia, Teixeira João Paulo, Moreira André, de Oliveira Fernandes Eduardo

机构信息

Faculty of Medicine of the University of Porto, Porto, Portugal.

S. João Hospital Centre, Porto, Portugal.

出版信息

Porto Biomed J. 2016 Sep-Oct;1(4):142-146. doi: 10.1016/j.pbj.2016.07.003. Epub 2016 Aug 10.

DOI:10.1016/j.pbj.2016.07.003
PMID:32258565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6806995/
Abstract

HIGHLIGHTS

The SINPHONIE guidelines were successful in reducing PM and PM in schools.The schools failed to reduce the levels of other IAQ pollutants.No significant changes were observed in the prevalence of atopy.

BACKGROUND

The onset and exacerbation of allergic diseases and asthma have been associated with poor indoor air quality (IAQ) inside classrooms.

OBJECTIVE

The aim was to investigate how IAQ changed in primary schools after applying indoor air quality recommendations, and to explore how these changes influenced allergic sensitization on children.

METHODS

Total volatile organic compounds, PM, PM, CO, CO, temperature and relative humidity in the indoor and outdoor air of 20 primary schools were measured in 2010-2012. The school staff received instructions on how to improve IAQ in accordance with the dedicated guidelines. Atopy status was assessed in children attending the participating classrooms by skin prick tests and exhaled nitric oxide. A follow-up sampling campaign was performed in 2014-2015 in the same schools.

RESULTS

Indoor PM and PM concentrations were approximately 40% lower in the follow-up measurements ( < 0.05). There were no significant differences regarding outdoor PM concentrations. Nevertheless, PM levels from the follow-up campaign still exceeded the reference value established by Portuguese legislation. Moreover, there were no significant differences in atopic prevalence and FENO values between the campaigns.

CONCLUSION

These findings suggest that adoption of the recommendations based on the SINPHONIE guidelines was particularly successful in reducing PM and PM in primary schools of Porto. Nevertheless, the schools failed to reduce the levels of other IAQ pollutants, as well as the prevalence of atopic disease.

摘要

要点

SINPHONIE指南在降低学校内的细颗粒物(PM)和可吸入颗粒物(PM)方面取得了成功。学校未能降低其他室内空气质量污染物的水平。特应性疾病的患病率未观察到显著变化。

背景

过敏性疾病和哮喘的发作及加重与教室内不良的室内空气质量(IAQ)有关。

目的

旨在调查应用室内空气质量建议后小学室内空气质量如何变化,并探讨这些变化如何影响儿童的过敏性致敏。

方法

在2010 - 2012年期间对20所小学的室内外空气中的总挥发性有机化合物、PM、PM、一氧化碳(CO)、二氧化碳(CO₂)、温度和相对湿度进行了测量。学校工作人员收到了根据专门指南改善室内空气质量的指导。通过皮肤点刺试验和呼出一氧化氮对参与教室的儿童的特应性状态进行了评估。2014 - 2015年在同一学校进行了后续采样活动。

结果

在后续测量中,室内PM和PM浓度降低了约40%(P < 0.05)。室外PM浓度没有显著差异。然而,后续活动中的PM水平仍超过了葡萄牙立法规定的参考值。此外,两次活动之间特应性患病率和呼出一氧化氮(FENO)值没有显著差异。

结论

这些发现表明,采用基于SINPHONIE指南的建议在降低波尔图小学的PM和PM方面特别成功。然而,学校未能降低其他室内空气质量污染物的水平以及特应性疾病的患病率。

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