Bayraktar Fatih Avni, Mete Muge Tasdemir, Sargin Murat, Erdogan Sevinc Bayer, Bastopcu Murat, Yildirimturk Ozlem, Orhan Gokcen, Aka Serap Aykut
Department of Cardiovascular Surgery, Mus State Hospital, Mus, Turkey.
Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Reserch Hospital, Istanbul, Turkey.
North Clin Istanb. 2019 Jul 8;7(2):106-111. doi: 10.14744/nci.2019.75002. eCollection 2020.
Pump thrombosis in left ventricular assist device (LVAD) patients is an important cause of mortality and morbidity. Inflow cannula migration is a predisposing factor for pump thrombosis. Telecardiographic measurements can be used to follow up apical cannula deviation. In this study, we aimed to evaluate the migration of the inflow cannulas in patients with LVADs using angle measurements on telecardiograms.
Twenty-three patients who were implanted left ventricular assist devices in our clinic between February 2013 and April 2016 were included in our study. During the first year of follow-up, changes in angle measurements on postoperative 1, 3, 6, and 12 month telecardiograms were compared against the incidence of device thrombus and serum Lactate Dehydrogenase (LDH) levels.
Patients who were diagnosed with device thrombosis had more change in inflow cannula angles than patients without device thrombus (p<0.05 at 6 and 12 months). Patients with higher LDH values had more parallel angular changes at all intervals, and the change in angle was statistically significant at 3, 6 and 12 months (p<0.05).
This study shows that it is possible to track the migration of inflow cannulas in patients with left ventricular heart failure using telecardiograms. The correlation between angle change and LDH levels and embolic events may suggest that telecardiographic follow up of angles may be a useful tool for ventricular assist devices teams for early detection of thrombus.
左心室辅助装置(LVAD)患者发生泵血栓形成是死亡率和发病率的重要原因。流入插管移位是泵血栓形成的一个诱发因素。远程心电图测量可用于随访心尖插管移位情况。在本研究中,我们旨在通过远程心电图上的角度测量来评估LVAD患者流入插管的移位情况。
纳入2013年2月至2016年4月在我院植入左心室辅助装置的23例患者。在随访的第一年,将术后1、3、6和12个月远程心电图上角度测量的变化与装置血栓形成的发生率和血清乳酸脱氢酶(LDH)水平进行比较。
诊断为装置血栓形成的患者流入插管角度的变化比未发生装置血栓的患者更大(6个月和12个月时p<0.05)。LDH值较高的患者在所有时间段角度变化更平行,且在3、6和12个月时角度变化具有统计学意义(p<0.05)。
本研究表明,使用远程心电图可以追踪左心室心力衰竭患者流入插管的移位情况。角度变化与LDH水平及栓塞事件之间的相关性可能表明,对角度进行远程心电图随访可能是心室辅助装置团队早期检测血栓的有用工具。