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减数分裂:位置、位置、位置,交叉互换如何确保分离。

Meiosis: Location, Location, Location, How Crossovers Ensure Segregation.

机构信息

Stowers Institute for Medical Research, 1000 E. 50(th) St., Kansas City, MO 64110, USA.

Stowers Institute for Medical Research, 1000 E. 50(th) St., Kansas City, MO 64110, USA; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.

出版信息

Curr Biol. 2020 Apr 6;30(7):R311-R313. doi: 10.1016/j.cub.2020.02.020.

DOI:10.1016/j.cub.2020.02.020
PMID:32259504
Abstract

The proper behavior of homologous chromosomes at the first meiotic division is usually ensured by crossing over. A new study shows that crossover position influences the successful completion of the chromatin remodeling processes that facilitate homologous segregation.

摘要

同源染色体在第一次减数分裂中的正确行为通常由交叉互换来保证。一项新的研究表明,交叉互换的位置会影响促进同源分离的染色质重塑过程的顺利完成。

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1
Meiosis: Location, Location, Location, How Crossovers Ensure Segregation.减数分裂:位置、位置、位置,交叉互换如何确保分离。
Curr Biol. 2020 Apr 6;30(7):R311-R313. doi: 10.1016/j.cub.2020.02.020.
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Chromosome-wide control of meiotic crossing over in C. elegans.秀丽隐杆线虫减数分裂交叉的全染色体控制
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Where to cross? New insights into the location of meiotic crossovers.在哪里交叉?减数分裂交叉位置的新见解。
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Distributing meiotic crossovers for optimal fertility and evolution.为了最佳的生育力和进化而分配减数分裂的交叉。
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Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus.降低 MSH4 拷贝数可防止油菜中非同源染色体间的减数分裂交叉。
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Variation in crossover frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiae.交叉频率的变化扰乱了交叉保证,而不影响酿酒酵母中的减数分裂染色体分离。
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Chromosome axis defects induce a checkpoint-mediated delay and interchromosomal effect on crossing over during Drosophila meiosis.染色体轴缺陷在果蝇减数分裂过程中诱导一个检查点介导的延迟和染色体间的交叉效应。
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ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegans.ZHP-3在秀丽隐杆线虫的交叉点发挥作用,将减数分裂重组与联会复合体解体及二价体形成联系起来。
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The spindle checkpoint rescues the meiotic segregation of chromosomes whose crossovers are far from the centromere.纺锤体检查点挽救了交叉远离着丝粒的染色体的减数分裂分离。
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Homologous chromosome interactions in meiosis: diversity amidst conservation.减数分裂中的同源染色体相互作用:保守中的多样性
Nat Rev Genet. 2005 Jun;6(6):477-87. doi: 10.1038/nrg1614.

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Mol Ecol. 2025 Feb;34(3):e17627. doi: 10.1111/mec.17627. Epub 2024 Dec 17.
2
COSA-1 mediated pro-crossover complex formation promotes meiotic crossing over in C. elegans.COSA-1 介导的前交叉复合物形成促进了秀丽隐杆线虫减数分裂的交叉。
Nucleic Acids Res. 2024 May 8;52(8):4375-4392. doi: 10.1093/nar/gkae130.
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DNA/RNA helicase DHX36 is required for late stages of spermatogenesis.
DNA/RNA 解旋酶 DHX36 是精子发生晚期所必需的。
J Mol Cell Biol. 2023 Apr 6;14(11). doi: 10.1093/jmcb/mjac069.
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Meiotic, genomic and evolutionary properties of crossover distribution in Drosophila yakuba.减数分裂、基因组和果蝇 yakuba 中交叉分布的进化特性。
PLoS Genet. 2022 Mar 23;18(3):e1010087. doi: 10.1371/journal.pgen.1010087. eCollection 2022 Mar.