[再生医学中的干细胞——从实验室到临床应用]
[Stem cells in regenerative medicine - from bench to bedside].
作者信息
Klietz Marie-Luise, Kückelhaus Maximilian, Kaiser Hans Wilhelm, Raschke Michael J, Hirsch Tobias, Aitzetmüller Matthias
机构信息
Abteilung für Plastische-, Rekonstruktive und Ästhetische Chirurgie, Handchirurgie, Fachklinik Hornheide, Münster.
Sektion Plastische Chirurgie an der Klinik für Unfall-, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Münster, Münster.
出版信息
Handchir Mikrochir Plast Chir. 2020 Aug;52(4):338-349. doi: 10.1055/a-1122-8916. Epub 2020 Apr 7.
The use of mesenchymal stem cells for regenerative medicine is becoming more popular than ever before - even though their clinical usage is limited. Many ethical and translational questions, as well as legal aspects and uncertainty regarding safety inhibit the growth of appropriate therapies from promising scientific approaches.This paper demonstrates the main problems of the translation from stem cell based therapies from basic science towards their clinical use.
间充质干细胞在再生医学中的应用正变得比以往任何时候都更受欢迎——尽管它们的临床应用有限。许多伦理和转化问题，以及法律方面和安全性的不确定性，阻碍了从有前景的科学方法发展出合适的治疗方法。本文阐述了从基于干细胞的疗法从基础科学向临床应用转化过程中的主要问题。
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