Zhang Jia, Wang Yuhua, Xu Zhigang, Zhang Haixia, Dong Pengyu, Guo Linna, Li Fenghua, Xin Shuangyu, Zeng Wei
Department of Materials Science, School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, P. R. China.
J Mater Chem B. 2013 Jan 21;1(3):330-338. doi: 10.1039/c2tb00045h. Epub 2012 Nov 8.
In this paper, size-controlled morphologies of (Y, Gd)VO and (Y, Gd)VO:Ln (Ln = Eu, Yb, Er, and Ho) were obtained via a facile hydrothermal route, and their properties for drug delivery and photoluminescence were investigated. Monodisperse ellipsoid-like hollow (Y, Gd)VO were designed by employing (Y, Gd)(OH)CO colloidal spheres as a sacrificial template and NHVO as a vanadium source, and the formation mechanism could be interpreted by the Kirkendall effect. The control of particle size for hollow (Y, Gd)VO was realized, facilitating their practical application. Mesoporous core-shell structured (Y, Gd)VO:Ln@nSiO@mSiO were designed to improve the properties for drug release. Typically, red emission of YVO:Eu predominated under 465 nm excitation; the upconversion spectra of YVO:Yb, Er and YVO:Yb, Ho revealed green and red color upon 980 nm excitation, respectively. The biocompatibility and drug release evaluations indicate the potential biological applications of the samples.
在本文中，通过简便的水热法获得了尺寸可控的(Y, Gd)VO和(Y, Gd)VO:Ln（Ln = Eu、Yb、Er和Ho）的形貌，并研究了它们的药物递送和光致发光性能。通过使用(Y, Gd)(OH)CO胶体球作为牺牲模板和NHVO作为钒源，设计出了单分散的椭球状空心(Y, Gd)VO，其形成机制可以用柯肯达尔效应来解释。实现了对空心(Y, Gd)VO粒径的控制，有利于其实际应用。设计了介孔核壳结构的(Y, Gd)VO:Ln@nSiO@mSiO以改善药物释放性能。通常，在465 nm激发下，YVO:Eu以红色发射为主；在980 nm激发下，YVO:Yb, Er和YVO:Yb, Ho的上转换光谱分别显示出绿色和红色。生物相容性和药物释放评估表明了样品潜在的生物学应用。
