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一种用于共同递送临床相关奥沙利铂和吉西他滨的可生物降解聚合物平台。

A biodegradable polymer platform for co-delivery of clinically relevant oxaliplatin and gemcitabine.

作者信息

Song Haiqin, Xiao Haihua, Zheng Minhua, Qi Ruogu, Yan Lesan, Jing Xiabin

机构信息

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

出版信息

J Mater Chem B. 2014 Oct 14;2(38):6560-6570. doi: 10.1039/c4tb00678j. Epub 2014 Aug 26.

DOI:10.1039/c4tb00678j
PMID:32261817
Abstract

Anticancer drugs of gemcitabine and oxaliplatin combined in a clinic regimen (GEMOX regimen) were co-loaded to a biodegradable polymer platform for drug delivery.

摘要

将用于临床方案（GEMOX方案）的抗癌药物吉西他滨和奥沙利铂共同负载到用于药物递送的可生物降解聚合物平台上。

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A biodegradable polymer platform for co-delivery of clinically relevant oxaliplatin and gemcitabine.一种用于共同递送临床相关奥沙利铂和吉西他滨的可生物降解聚合物平台。
J Mater Chem B. 2014 Oct 14;2(38):6560-6570. doi: 10.1039/c4tb00678j. Epub 2014 Aug 26.
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Safety and efficacy of single-day GemOx regimen in patients with pancreatobiliary cancer: a single institution experience.单日内 GemOx 方案治疗胰胆肿瘤患者的安全性和疗效：单机构经验。
Expert Opin Drug Saf. 2010 Mar;9(2):207-13. doi: 10.1517/14740330903555181.
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Co-delivery of daunomycin and oxaliplatin by biodegradable polymers for safer and more efficacious combination therapy.可生物降解聚合物共递送阿霉素和奥沙利铂用于更安全、更有效的联合治疗。
J Control Release. 2012 Nov 10;163(3):304-14. doi: 10.1016/j.jconrel.2012.06.004. Epub 2012 Jun 12.
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[Efficacy of gemcitabine combined oxaliplatin on advanced pancreatic cancer].吉西他滨联合奥沙利铂治疗晚期胰腺癌的疗效
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[Efficacy and safety evaluation of gemcitabine combined with oxaliplatin in lymphoma patients after failure of multiple chemotherapy regimens].吉西他滨联合奥沙利铂对多程化疗方案失败的淋巴瘤患者的疗效及安全性评估
Zhonghua Zhong Liu Za Zhi. 2014 Feb;36(2):137-40.
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Evaluation of the combination of oxaliplatin and 5-fluorouracil or gemcitabine in patients with sporadic metastatic pulmonary carcinoid tumors.奥沙利铂与5-氟尿嘧啶或吉西他滨联合应用于散发性转移性肺类癌患者的疗效评估。
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Efficacy of the GemOx-R regimen leads to the identification of Oxaliplatin as a highly effective drug against Mantle Cell Lymphoma.GemOx-R方案的疗效使奥沙利铂被认定为一种治疗套细胞淋巴瘤的高效药物。
Br J Haematol. 2016 Sep;174(6):899-910. doi: 10.1111/bjh.14141. Epub 2016 May 25.
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Gemcitabine plus oxaliplatin combination (GEMOX regimen) in pretreated patients with advanced non-small cell lung cancer (NSCLC): a multicenter phase II study.吉西他滨联合奥沙利铂方案（GEMOX方案）用于晚期非小细胞肺癌（NSCLC）经治患者：一项多中心II期研究。
Lung Cancer. 2006 Dec;54(3):347-52. doi: 10.1016/j.lungcan.2006.09.001. Epub 2006 Oct 9.
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Addition of an antiangiogenic therapy, bevacizumab, to gemcitabine plus oxaliplatin improves survival in advanced biliary tract cancers.贝伐珠单抗联合吉西他滨和顺铂治疗晚期胆道癌可提高生存率。
Invest New Drugs. 2018 Feb;36(1):156-162. doi: 10.1007/s10637-017-0492-6. Epub 2017 Aug 1.
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Experience of gemcitabine plus oxaliplatin chemotherapy in patients with advanced biliary tract carcinoma.吉西他滨联合奥沙利铂化疗治疗晚期胆道癌患者的经验。
Chemotherapy. 2010;56(3):234-8. doi: 10.1159/000316848. Epub 2010 Jun 16.

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