Miller Philip R, Narayan Roger J, Polsky Ronen
Sandia National Laboratories, Albuquerque, New Mexico 87185, USA.
J Mater Chem B. 2016 Feb 28;4(8):1379-1383. doi: 10.1039/c5tb02421h. Epub 2016 Jan 21.
Recently microneedles have been explored for transdermal monitoring of biomarkers with the goal to achieve time-sensitive clinical information for routine point-of-care health monitoring. In this highlight we provide a general overview of recent progress in microneedle-based sensing research, including: (a) glucose monitoring, (b) ex vitro microneedle diagnostic systems for general health monitoring with an emphasis on sensor construction, and (c) in vivo use of microneedle sensors.
最近，人们对微针用于生物标志物的经皮监测进行了探索，目的是获取用于常规即时医疗健康监测的具有时间敏感性的临床信息。在本综述中，我们概述了基于微针的传感研究的最新进展，包括：（a）葡萄糖监测；（b）用于一般健康监测的离体微针诊断系统，重点是传感器构建；以及（c）微针传感器的体内应用。
