Dai Jianyuan, He Hongfei, Duan Zhijuan, Zhou Cuisong, Long Yuyin, Zheng Baozhan, Du Juan, Guo Yong, Xiao Dan
College of Chemistry, Sichuan University, Chengdu 610064, China.
J Mater Chem B. 2016 May 21;4(19):3191-3194. doi: 10.1039/c6tb00029k. Epub 2016 Apr 5.
A novel target-triggered DNA autonomous assembly pathway for the formation of one-dimensional DNA polymer chains was proposed based on the catalyzed hairpin assembly and sticky end self-assembly, which led to an enzyme-free and signal amplified gold nanoparticle (AuNP) based colorimetric nucleic acid assay with picomolar sensitivity and specificity.
基于催化发夹组装和粘性末端自组装，提出了一种用于形成一维DNA聚合物链的新型靶标触发DNA自主组装途径，该途径导致了一种基于金纳米颗粒（AuNP）的无酶且信号放大的比色核酸检测方法，具有皮摩尔级的灵敏度和特异性。
