Cui Dong, Xie Chen, Lyu Yan, Zhen Xu, Pu Kanyi
School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457, Singapore.
J Mater Chem B. 2017 Jun 21;5(23):4406-4409. doi: 10.1039/c6tb03393h. Epub 2017 Feb 15.
Development of photoacoustic (PA) imaging agents is crucial to advancing PA imaging in biology and medicine. In this study, we report the design and synthesis of near-infrared (NIR) absorbing amphiphilic semiconducting polymers that can spontaneously self-assemble into homogeneous water-soluble nanoparticles for PA imaging of tumor in living mice.
光声(PA)成像剂的开发对于推动生物学和医学中的PA成像至关重要。在本研究中,我们报告了近红外(NIR)吸收两亲性半导体聚合物的设计与合成,该聚合物可自发自组装成均匀的水溶性纳米颗粒,用于活体小鼠肿瘤的PA成像。