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老年桡骨远端骨折患者的营养状况与功能预后:一项回顾性队列研究。

Nutrition status and functional prognosis among elderly patients with distal radius fracture: a retrospective cohort study.

机构信息

Department of Rehabilitation Medicine, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo, 1018309, Japan.

Department of Orthopedic Surgery, Osumi Hospital, Tokyo, Japan.

出版信息

J Orthop Surg Res. 2020 Apr 7;15(1):133. doi: 10.1186/s13018-020-01657-y.

Abstract

BACKGROUND

Distal radius fractures (DRF) are common in the elderly and are typically caused falls. Malnutrition has also been identified as a poor prognostic factor in elderly patients with fractures. However, the relationship between nutritional status and subsequent falls and functional prognosis for DRF in the elderly is not clear. The aim of the present study was to investigate the association between nutritional status and functional prognosis in elderly patients with DRF.

METHODS

Study participants included 229 outpatients who required surgical treatment for DRF. The patients' clinical information, including age, sex, body mass index, bone mineral density, geriatric nnutritional risk index (GNRI), total number of drugs being treated with on admission, use of drugs for osteoporosis, comorbidity severity, the Barthel Index (BI), presence of subsequent falls, fracture type, postoperative follow-up period, and Mayo wrist score was reviewed. Subjects were further divided into two groups according to their GNRI: the malnutrition group and the normal group. Propensity score matching was used to confirm factors affecting the BI and subsequent falls.

RESULTS

Thirty-one patients (13.5%) presented with malnutrition before surgery for DRF. According to multiple liner regression analysis, the GNRI positively affected the efficiency of the BI (β = 0.392, 95% confidence interval [CI], 0.001 to 0.351, p = 0.039). Furthermore, on logistic regression analysis, subsequent falls were associated with serum albumin levels (odds ratio = 0.033, 95% CI, 0.002 to 0.477, p = 0.012).

CONCLUSION

Malnutrition impaired improvement of activities of daily living (ADL) and increased the incidence of subsequent falls. Improvement of nutritional status before DRF surgery may further improve ADL and prevent falls.

摘要

背景

桡骨远端骨折(DRF)在老年人中较为常见,通常由跌倒引起。营养不良也被确定为老年骨折患者的预后不良因素。然而,营养状况与老年人 DRF 随后跌倒和功能预后之间的关系尚不清楚。本研究旨在探讨营养状况与 DRF 老年患者功能预后的关系。

方法

研究对象包括 229 名需要手术治疗 DRF 的门诊患者。回顾了患者的临床信息,包括年龄、性别、体重指数、骨密度、老年营养风险指数(GNRI)、入院时治疗的药物总数、骨质疏松症药物的使用、合并症严重程度、巴氏指数(BI)、是否发生后续跌倒、骨折类型、术后随访期和 Mayo 腕关节评分。根据 GNRI 将受试者进一步分为营养不良组和正常组。使用倾向评分匹配来确认影响 BI 和后续跌倒的因素。

结果

31 例(13.5%)DRF 术前存在营养不良。根据多元线性回归分析,GNRI 对 BI 的效率有积极影响(β=0.392,95%置信区间[CI],0.001 至 0.351,p=0.039)。此外,在逻辑回归分析中,随后的跌倒与血清白蛋白水平有关(比值比=0.033,95%CI,0.002 至 0.477,p=0.012)。

结论

营养不良会降低日常生活活动(ADL)的改善程度,并增加随后跌倒的发生率。在 DRF 手术前改善营养状况可能进一步改善 ADL 并预防跌倒。

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