Liu Steven H, Cerri-Droz Patricia, Loyst Rachel A, Warheit Zachary, Komatsu David E, Wang Edward D
Department of Orthopaedics, Stony Brook University, Stony Brook, New York.
J Wrist Surg. 2024 Mar 8;14(3):239-245. doi: 10.1055/s-0044-1782239. eCollection 2025 Jun.
While previous studies have investigated the association between the Geriatric Nutritional Risk Index (GNRI) and functional outcomes following distal radius fracture (DRF), no large-scale studies have investigated the associations between GNRI and postoperative outcomes following DRFs. The purpose of this study is to investigate the association between GNRI, a simple multifaceted measure of malnutrition risk, and 30-day postoperative complications following DRF open reduction internal fixation (ORIF). The American College of Surgeons National Surgical Quality Improvement Program database was queried for patients who underwent DRF ORIF from 2015 to 2021. Patients were organized into three groups based on preoperative GNRI: normal/reference (GNRI > 98), moderate malnutrition (92 ≤ GNRI ≤ 98), and severe malnutrition (GNRI < 92). Logistic regression analysis was conducted to investigate the relationship between preoperative GNRI and postoperative complications. Severe malnutrition was independently associated with a greater likelihood of any complication (odds ratio [OR]: 3.22, 95% confidence interval [CI]: 2.48-4.17; < 0.001), sepsis (OR: 15.41, 95% CI: 1.66-143.32; = 0.016), cardiac arrest or myocardial infarction (OR: 20.58, 95% CI: 1.62-261.26; = 0.020), pulmonary embolism (OR: 9.40, 95% CI: 1.76-50.11; = 0.009), surgical site infection (OR: 7.73, 95% CI: 1.99-30.02; = 0.003), nonhome discharge (OR: 2.55, 95% CI: 1.87-3.49; < 0.001), readmission (OR: 2.47, 95% CI: 1.47-4.14; < 0.001), and length of stay > 2 days (OR: 3.51, 95% CI: 2.67-4.62; < 0.001). Malnutrition is an independent significant predictor of early complications following DRF ORIF. Level III; retrospective cohort comparison; prognosis study.
虽然先前的研究调查了老年营养风险指数(GNRI)与桡骨远端骨折(DRF)后功能结局之间的关联,但尚无大规模研究调查GNRI与DRF术后结局之间的关联。本研究的目的是调查GNRI(一种简单的多方面营养不良风险测量方法)与DRF切开复位内固定术(ORIF)后30天术后并发症之间的关联。查询了美国外科医师学会国家外科质量改进计划数据库中2015年至2021年接受DRF ORIF的患者。根据术前GNRI将患者分为三组:正常/参照组(GNRI>98)、中度营养不良组(92≤GNRI≤98)和重度营养不良组(GNRI<92)。进行逻辑回归分析以研究术前GNRI与术后并发症之间的关系。重度营养不良与任何并发症(优势比[OR]:3.22,95%置信区间[CI]:2.48 - 4.17;P<0.001)、脓毒症(OR:15.41,95%CI:1.66 - 143.32;P = 0.016)、心脏骤停或心肌梗死(OR:20.58,95%CI:1.62 - 261.26;P = 0.020)、肺栓塞(OR:9.40,95%CI:1.76 - 50.11;P = 0.009)、手术部位感染(OR:7.73,95%CI:1.99 - 30.02;P = 0.003)、非家庭出院(OR:2.55,95%CI:1.87 - 3.49;P<0.001)、再入院(OR:2.47,95%CI:1.47 - 4.14;P<0.001)以及住院时间>2天(OR:3.51,95%CI:2.67 - 4.62;P<0.001)的可能性更大独立相关。营养不良是DRF ORIF术后早期并发症的独立显著预测因素。三级;回顾性队列比较;预后研究。